Background/Aim: While there has been a rapid development in genomic data mining
approaches for T-cell receptor recombinations (TcR), less emphasis has been placed on B …

Tumor exomes and RNASeq data were originally intended for obtaining tumor mutations
and gene expression profiles, respectively. However, recent work has determined that tumor …

Understanding tumor-resident T cells is important for cancer prognosis and treatment
options. Conventional, solid tumor specimen exome files can be searched directly for …

Simple Summary Human cancer genomes show a variety of alterations, such as single base
changes, deletions, insertions, copy number changes, and gene fusions. Analyzing fusion …

Era of comprehensive cancer genome analyses. - Abstract - Europe PMC Sign in | Create an
account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us …

Background: Lung cancer (LC) is the dominant cause of death by cancer in the world, being
responsible for more than a million deaths annually. It is a highly lethal common tumor that is …

Gene fusions, like BCR/ABL1 in chronic myelogenous leukemia, have long been recognized
in hematologic and mesenchymal malignancies. The recent finding of gene fusions in …

Abstract Background/Aim: Lung cancer remains the main culprit in cancer-related mortality
worldwide. Transcript fusions play a critical role in the initiation and progression of multiple …

The ability to identify the broadest range of targetable gene fusions is crucial to facilitate
personalized therapy selection for advanced lung adenocarcinoma (LuADs) patients …

We assessed pancreatic cancer, lymphocyte infiltrates with a computational genomics
approach. We took advantage of tumor-specimen exome files available from the cancer …