Eribulin promotes antitumor immune responses in patients with locally advanced or metastatic breast cancer
W Goto, S Kashiwagi, Y Asano, K Takada… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Several proteins involved in immune regulation and the relationship
among these, the tumor microenvironment, and clinical outcomes of eribulin treatment were …
among these, the tumor microenvironment, and clinical outcomes of eribulin treatment were …
Validation of systemic and local tumour immune response to eribulin chemotherapy in the treatment of breast cancer
S Kashiwagi, Y Asano, W Goto, K Takada… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: In addition to its cytocidal effects as a microtubule dynamics inhibitor,
eribulin mesylate (eribulin) regulates the tumour microenvironment. We examined the …
eribulin mesylate (eribulin) regulates the tumour microenvironment. We examined the …
A maintained absolute lymphocyte count predicts the overall survival benefit from eribulin therapy, including eribulin re-administration, in HER2-negative advanced …
J Watanabe, M Saito, Y Horimoto… - Breast Cancer Research …, 2020 - Springer
Purpose Eribulin methylate (eribulin) improved the overall survival (OS) of HER2-negative
advanced breast cancer (HER2− ABC) patients; however, the mechanism underlying the OS …
advanced breast cancer (HER2− ABC) patients; however, the mechanism underlying the OS …
[HTML][HTML] Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to …
T Yoshida, Y Ozawa, T Kimura, Y Sato… - British journal of …, 2014 - nature.com
Background: Eribulin mesilate (eribulin), a non-taxane microtubule dynamics inhibitor, has
shown trends towards greater overall survival (OS) compared with progression-free survival …
shown trends towards greater overall survival (OS) compared with progression-free survival …
Mesenchymal–epithelial transition and tumor vascular remodeling in eribulin chemotherapy for breast cancer
S Kashiwagi, Y Asano, W Goto, K Takada… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Eribulin mesylate (eribulin) is currently used for the treatment of locally
advanced or metastatic breast cancer (MBC). It is a cytotoxic agent with unique mechanisms …
advanced or metastatic breast cancer (MBC). It is a cytotoxic agent with unique mechanisms …
Antitumor and anticancer stem cell activities of eribulin mesylate and antiestrogens in breast cancer cells
J Kurebayashi, N Kanomata, T Yamashita, T Shimo… - Breast Cancer, 2016 - Springer
Background Eribulin mesylate (eribulin), a non-taxane microtubule dynamic inhibitor, has
been widely used in the treatment of patients with advanced or metastatic breast cancer. The …
been widely used in the treatment of patients with advanced or metastatic breast cancer. The …
[HTML][HTML] High absolute lymphocyte counts are associated with longer overall survival in patients with metastatic breast cancer treated with eribulin—but not with …
Y Miyoshi, Y Yoshimura, K Saito, K Muramoto… - Breast Cancer, 2020 - Springer
Background Eribulin, a nontaxane synthetic inhibitor of microtubule dynamics, is widely
used to manage locally advanced or metastatic breast cancer (MBC). Eribulin has …
used to manage locally advanced or metastatic breast cancer (MBC). Eribulin has …
Perspectives on the mechanism of action and clinical application of eribulin for metastatic breast cancer
J O'Shaughnessy, V Kaklamani, K Kalinsky - Future Oncology, 2019 - Future Medicine
Eribulin is a novel microtubule inhibitor with mitotic and nonmitotic mechanisms of action.
Both pooled and subgroup analyses from large-scale Phase III clinical trials demonstrated …
Both pooled and subgroup analyses from large-scale Phase III clinical trials demonstrated …
[HTML][HTML] Investigating the Role of CTCs with Stem/EMT-like Features in Metastatic Breast Cancer Patients Treated with Eribulin Mesylate
MA Papadaki, A Mala, AC Merodoulaki… - Cancers, 2022 - mdpi.com
Simple Summary Eribulin mesylate, an anti-mitotic drug used for the treatment of metastatic
breast cancer (BC), exhibits significant effects on cancer cell migration, invasion, and …
breast cancer (BC), exhibits significant effects on cancer cell migration, invasion, and …
[HTML][HTML] Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer
S Kashiwagi, W Fukushima, Y Asano, W Goto… - BMC cancer, 2017 - Springer
Background The recently developed reagent, eribulin mesylate (eribulin), is a microtubule
dynamics inhibitor with a mechanism of action that differs from those of taxanes and vinca …
dynamics inhibitor with a mechanism of action that differs from those of taxanes and vinca …
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