Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase-and mitochondrial-dependent signaling pathways
TH Ying, CW Chen, YP Hsiao, SJ Hung… - Anticancer …, 2013 - ar.iiarjournals.org
Citric acid is an alpha-hydroxyacid (AHA) widely used in cosmetic dermatology and skincare
products. However, there is concern regarding its safety for the skin. In this study, we …
products. However, there is concern regarding its safety for the skin. In this study, we …
Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes
Sanguinarine, derived from the root of Sanguinaria canadensis and other poppy fumaria
species, possesses strong antimicrobial, anti-inflammatory, and antioxidant properties. We …
species, possesses strong antimicrobial, anti-inflammatory, and antioxidant properties. We …
Baicalein induces apoptosis in SCC-4 human tongue cancer cells via a Ca2+-dependent mitochondrial pathway
Background: The effects of baicalein on SCC-4 human tongue cancer cells were examined
to better understand its effect on apoptosis and associated possible signal pathways in vitro …
to better understand its effect on apoptosis and associated possible signal pathways in vitro …
[PDF][PDF] Syringic acid suppresses oral squamous cell carcinoma SCC131 cell proliferation via modulation of mitochondria-mediated apoptosis signaling pathways
P Velu, A Vijayalakshmi, V Vinothkumar - J Biochem Mol Toxicol, 2020 - researchgate.net
Apoptosis is an important process of cell death that controls the intrinsic and extrinsic
pathways. Syringic acid (SRA)—a phenolic compound well‐known in traditional Indian …
pathways. Syringic acid (SRA)—a phenolic compound well‐known in traditional Indian …
Molecular mechanism of black tea polyphenols induced apoptosis in human skin cancer cells: involvement of Bax translocation and mitochondria mediated death …
B Halder, U Bhattacharya, S Mukhopadhyay… - …, 2008 - academic.oup.com
Theaflavins (TF) and thearubigins (TR) are the most exclusive polyphenols of black tea.
Even though few previous reports showed the anticancer effects of TF through apoptosis, the …
Even though few previous reports showed the anticancer effects of TF through apoptosis, the …
[HTML][HTML] Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun …
HY Shim, JH Park, HD Paik, SY Nah, DSHL Kim… - Molecules and cells, 2007 - Elsevier
The mechanism of acacetin-induced apoptosis of human breast cancer MCF-7 cells was
investigated. Acacetin caused 50% growth inhibition (IC 50) of MCF-7 cells at 26.4±0.7 μM …
investigated. Acacetin caused 50% growth inhibition (IC 50) of MCF-7 cells at 26.4±0.7 μM …
[HTML][HTML] Betulinic acid induces apoptosis by regulating PI3K/Akt signaling and mitochondrial pathways in human cervical cancer cells
T Xu, Q Pang, Y Wang, X Yan - … journal of molecular …, 2017 - spandidos-publications.com
Betulinic acid (BA), a potential anticancer compound, could induce apoptosis in human
cervical cancer (HeLa) cells, but its mechanism has yet to be fully elucidated. The present …
cervical cancer (HeLa) cells, but its mechanism has yet to be fully elucidated. The present …
Chelerythrine hydrochloride inhibits proliferation and induces mitochondrial apoptosis in cervical cancer cells via PI3K/BAD signaling pathway
T Yang, R Xu, Q Su, H Wang, F Liu, B Dai, B Wang… - Toxicology in Vitro, 2020 - Elsevier
Cervical cancer is the fourth most common female cancer worldwide, and drug targeted
therapy plays a crucial role in delaying the progression of cervical carcinoma. Chelerythrine …
therapy plays a crucial role in delaying the progression of cervical carcinoma. Chelerythrine …
Berberine induced apoptosis via promoting the expression of caspase-8,-9 and-3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous …
Many phytochemicals have been recognized to have potential chemopreventive or
chemotherapeutic efficacy in cancer treatment. In this study, we hypothesized that berberine …
chemotherapeutic efficacy in cancer treatment. In this study, we hypothesized that berberine …
Gambogenic acid mediated apoptosis through the mitochondrial oxidative stress and inactivation of Akt signaling pathway in human nasopharyngeal carcinoma CNE …
In the present study, Gambogenic acid exhibits potential anti-tumor activity in several cancer
cell lines. However, Gambogenic acid-induced apoptosis mechanism is not well understood …
cell lines. However, Gambogenic acid-induced apoptosis mechanism is not well understood …
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