Background: Testicular germ cell tumours are the most common malignancies in young
males. Molecular biology studies of these tumours are often contradictory. Two histological …

Testicular germ cell tumors can be divided into three groups (infantile/prepubertal,
adolescent/young adult and spermatocytic seminoma), each with its own constellation of …

In this thesis three aspects of the biology of testicular germ cell tumors of adults (TGCTs) are
studied: the pathogenetic relationship of carcinoma in situ (CIS), seminoma (SE) and …

Testicular germ cell tumors (TGCTs) are a heterogeneous group of neoplasms (see Mostofi
et al. 1987; Ulbright and Roth 1987 for recent reviews). TGCTs of adults can be divided …

In essence, two models exist of the pathogenetic relationship between seminomas and
nonseminomatous germ cell tumors (NSGCTs). In the first model, the histogenesis of …

Within the human testis, three entities of germ cell tumours are distinguished: the teratomas
and yolk sac tumors of newborn and infants, the seminomas and nonseminomas of …

Testicular germ cell tumor (TGCT) is the most common tumor type among adolescent and
young adult males. Familial clustering and bilateral disease are suggestive of a genetic …

Testicular germ cell tumors (TGCTs) of adults and adolescents are thought to be derived
from primordial germ cells or gonocytes. TGCTs develop postpuberty from precursor lesions …

This article, written on the occasion of Dr. Avery Sandberg's 75th birthday, is intended to give
a general and short overview of the cytogenetic data about testicular germ cell tumors of …

The development of the human gonads is tightly regulated by the correct sequential
expression of many genes and hormonal activity. Disturbance of this regulation does not …