Background/Aim: The effect of pelvic neoadjuvant radiotherapy (nRT) for stage M1a rectal
adenocarcinoma patients treated with systemic therapy followed by proctectomy and …

Background/Aim: The role of neoadjuvant radiotherapy in the management of patients with
locally advanced rectal cancer (LARC) who have undergone neoadjuvant systemic therapy …

Background Neoadjuvant radiotherapy (RT) has been shown to improve local control;
however, whether it can improve overall survival (OS) in locally advanced rectal cancer …

Purpose To determine outcomes after adjuvant pelvic local radiation therapy (RT)+/−
concurrent chemotherapy for T1 and T2 rectal carcinomas treated with local excision or …

Objectives: This study aimed to determine whether perioperative pelvic radiotherapy (RT)
improves outcomes in stage IV rectal cancer patients treated with primary surgical resection …

Background Neoadjuvant therapy followed by radical surgery is recommended for locally
advanced rectal cancer (LARC). But radiotherapy can cause potential adverse effects. The …

Background Many data suggest that patients with low rectal adenocarcinoma who achieved
ypT0N0 status have improved survival and disease-free survival (DFS) compared to all other …

Abstract Background The National Comprehensive Cancer Network guidelines recommend
routine postoperative adjuvant radiotherapy and chemotherapy for patients with stage III …

Purpose The aim of this study is to review the contemporary evidence comparing
neoadjuvant radiotherapy (NRT) versus no radiotherapy (no RT) in patients with stage IV …

Background Neoadjuvant chemoradiotherapy (NACRT) and total mesorectal excision (TME)
are standard treatments of stage II/III locally advanced rectal cancer (LARC), currently. Here …