Cut-off Analysis of HLA-A and HLA-B/C Expression as a Potential Prognosticator of Favorable Survival in Patients With Metastatic Breast Cancer

S Stefanovic, R Wirtz, M Suetterlin, U Karic… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Loss of differentiation of breast cancer cells in association with a down-
regulated class I human leukocyte antigen (HLA) expression can lead to proliferation …

[HTML][HTML] Clinical implication of HLA class I expression in breast cancer

K Kaneko, S Ishigami, Y Kijima, Y Funasako, M Hirata… - BMC cancer, 2011 - Springer
Background Human leukocyte antigen (HLA)-class I molecules on tumor cells have been
regarded as crucial sites where cytotoxic T lymphocytes (CTL) can recognize tumor-specific …

Prognostic and clinical significance of human leukocyte antigen class I expression in breast cancer: a meta-analysis

W Qiao, Z Jia, W Guo, Q Liu, X Guo, M Deng - Molecular Diagnosis & …, 2023 - Springer
Background The value of human leukocyte antigen (HLA; also known as major
histocompatibility complex) class I expression for the prediction of breast cancer survival …

Co-expression of HLA-I loci improved prognostication in HER2+ breast cancers

JY Tsang, CS Ho, YB Ni, Y Shao, IK Poon… - Cancer Immunology …, 2020 - Springer
The underlying basis for cancer immune evasion is important for effective immunotherapy
and prognosis in breast cancers. Human leucocyte antigens (HLA)-I comprising three …

Can the HLA phenotype be used as a prognostic factor in breast carcinomas?

A Concha, T Cabrera, F Ruiz‐Cabello… - International journal of …, 1991 - Wiley Online Library
There is evidence indicating that changes in the expression of HLA‐ABC antigens can
modulate the biological behavior and metastatic potential of certain neoplasms. We studied …

Analysis and clinical relevance of human leukocyte antigen class I, heavy chain, and β2-microglobulin downregulation in breast cancer

A Morabito, B Dozin, S Salvi, G Pasciucco, G Balbi… - Human immunology, 2009 - Elsevier
Investigation is lacking regarding the clinical impact of human leukocyte antigen (HLA) class
I downregulation in breast cancer and results are inconsistent. In this study, we investigated …

[HTML][HTML] Expression of HLA class I is associated with immune cell infiltration and patient outcome in breast cancer

SH Han, M Kim, YR Chung, JW Woo, HY Choi… - Scientific Reports, 2022 - nature.com
Downregulation of human leukocyte antigen (HLA) class I is one mechanism of escaping
anti-tumor immunity by tumor cells. This study was conducted to compare HLA class I …

Immunocytochemical demonstration of down regulation of HLA class-I molecule expression in human metastatic breast carcinoma

M Saio, M Teicher, G Campbell, H Feiner… - Clinical & experimental …, 2004 - Springer
Deficient expression of HLA class-I molecules observed in many cancers is suggested to
influence both disease progression and potential efficacy of T cell-mediated immune …

Importance of HLA-G expression and tumor infiltrating lymphocytes in molecular subtypes of breast cancer

DD Dong, S Yie, K Li, F Li, Y Xu, G Xu, L Song… - Human immunology, 2012 - Elsevier
This study is aimed at investigating whether or not human leukocyte antigen-G (HLA-G)
expression is associated with breast cancer molecular subtypes. HLA-G expression was …

[HTML][HTML] Loss of human leukocyte antigen class I expression is associated with poor prognosis in patients with advanced breast cancer

HS Park, U Cho, SY Im, CY Yoo, JH Jung… - Journal of pathology …, 2019 - ncbi.nlm.nih.gov
Background Human leukocyte antigen class I (HLA-I) molecules play important roles in
regulating immune responses. Loss or reduction of HLA-I expression has been shown to be …