Lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma

S Arimoto, T Hasegawa, D Takeda, I Saito… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Tumor lymphangiogenesis plays a key role in lymph node (LN) metastasis
in oral squamous cell carcinoma (OSCC). The purpose of this study was to investigate …

Lymphangiogenesis and podoplanin expression in oral squamous cell carcinoma and the associated lymph nodes

SF De Sousa, FO Gleber-Netto… - Applied …, 2012 - journals.lww.com
The objective of this study was to evaluate lymphangiogenesis in oral squamous cell
carcinoma and in the associated lymph nodes and podoplanin expression in neoplastic …

[HTML][HTML] Immunohistochemical study of vascular endothelial growth factor‑C/vascular endothelial growth factor receptor‑3 expression in oral tongue squamous cell …

T Naruse, S Yanamoto, SI Yamada… - Oncology …, 2015 - spandidos-publications.com
The aim of the present study was to elucidate the associations between the expression of
the vascular endothelial growth factor‑C (VEGF‑C)/VEGF receptor‑3 (VEGFR‑3) axis and …

[HTML][HTML] Proliferating Lymphatic Endothelial Cells as a Prognostic Marker in Head and Neck Squamous Cell Carcinoma

CS Dumitru, AR Ceausu, NP Gaje, CS Suciu… - International Journal of …, 2022 - mdpi.com
Podoplanin and Ki-67 are two important markers of cancer progression. The aim of this
study is to evaluate double immunostaining for Ki-67 and podoplanin in head and neck …

Regional difference in intratumoral lymphangiogenesis of oral squamous cell carcinomas evaluated by immunohistochemistry using D2‐40 and podoplanin antibody …

F Ohno, H Nakanishi, A Abe, Y Seki… - Journal of oral …, 2007 - Wiley Online Library
Background: Whether tumor cells induce lymphangiogenesis intratumorally or permeate pre‐
existing lymphatic vessels in the peritumoral area still remains unclear. In this study, we …

[HTML][HTML] Assessment of podoplanin lymphatic vessel density in oral epithelial dysplasia

SD Lunawat, N Prakash, GL Pradeep… - Journal of Oral and …, 2021 - journals.lww.com
Background: Oral squamous cell carcinoma (OSCC) can be preceded by the appearance of
lesions which have the potential to develop into cancer. Recently, it was suggested that the …

[HTML][HTML] Primary tumor-secreted lymphangiogenic factors induce pre-metastatic lymphvascular niche formation at sentinel lymph nodes in oral squamous cell …

N Wakisaka, Y Hasegawa, S Yoshimoto, K Miura… - PLoS …, 2015 - journals.plos.org
Objectives The objectives of this study were to evaluate the formation of lymphvascular
niches in lymph nodes of patients with oral squamous cell carcinoma (OSCC), and …

[HTML][HTML] Role of podoplanin in potentially malignant disorders and oral squamous cell carcinoma and its correlation with lymphangiogenesis

S Parhar, H Kaur, A Vashist, S Verma - Indian journal of cancer, 2015 - journals.lww.com
BACKGROUND: Oral squamous cell carcinoma (OSCC) ranks as one of the most common
types of cancer and oral potentially malignant lesions (OPMLs) provides with an overall …

Expression analysis of lymphangiogenic factors in human colorectal cancer with quantitative RT-PCR

Y Lu, Q Yang, Y Du, G Feng, C Yang - Cancer investigation, 2007 - Taylor & Francis
Lymphatic spread of colorectal cancer cells to regional lymph nodes is one of the early
events in metastatic cancers and often is associated with distant metastatic spread and a …

Evidence for lymphangiogenesis and its prognostic implications in head and neck squamous cell carcinoma

PA Kyzas, S Geleff, A Batistatou… - The Journal of …, 2005 - Wiley Online Library
Lymph node metastasis is a frequent reason for adverse clinical outcome in many epithelial
neoplasms, including head and neck squamous cell carcinoma. The mechanisms …