Background: Human mesenchymal stem cells (MSCs) are thought to be multipotent cells
which primarily reside in the bone marrow. Besides their well-known ability to replicate as …

Bone marrow is a heterogeneous cell population which includes hematopoietic and
mesenchymal progenitor cells. Dysregulated hematopoiesis occurs in chronic myelogenous …

Background and objectives The role of bone marrow-mesenchymal stem cells (BM-MSC) in
leukaemic cell control is controversial. The purpose of this work was to evaluate BM-MSC …

OBJECTIVE: Mesenchymal stem cells (MSC) are promising candidates for cell-based
therapies. One major obstacle for their clinical use is the biosafety of fetal calf serum (FCS) …

Overwhelming evidence from leukemia research has shown that the clonal population of
neoplastic cells exhibits marked heterogeneity with respect to proliferation and …

Mesenchymal stem cells (MSCs) have received much attention for their ability to differentiate
into various cell types under specific conditions and to support the proliferation of …

Mesenchymal stem cells (MSCs) are of great therapeutic potential because of their ability to
self-renew and differentiate into multiple tissues. Compare to allogenetic MSCs, autologous …

Bone marrow (BM)-derived mesenchymal stromal cells (MSCs) frequently display alterations
in several hematologic disorders, such as acute lymphoid leukemia, acute myeloid leukemia …

Background The development of leukemia impairs normal hematopoiesis and marrow
stromal microenvironment. The aim of the investigation was to study the ability of multipotent …

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic
stem cells. It is characterized at cytogenetic level by the Philadelphia (Ph) chromosome and …