Gene expression of kallikreins in breast cancer cell lines

R Watrowski, DC Castillo-Tong, E Obermayr… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: This study analyzed the gene expression of the “classic” KLK1 and “new”
kallikreins KLK4-KLK15, in relation to the molecular characteristics and in vitro invasiveness …

Parallel underexpression of kallikrein 5 and kallikrein 7 mRNA in breast malignancies

X Li, J Liu, Y Wang, L Zhang, L Ning, Y Feng - Cancer science, 2009 - Wiley Online Library
Kallikrein (KLK) 5 and KLK7 were reported to be overexpressed in several cancers, but
underexpressed in prostate and breast cancers. However, the expression levels of KLK5 …

Specific increase of human kallikrein 4 mRNA and protein levels in breast cancer stromal cells

A Mangé, C Desmetz, ML Berthes… - Biochemical and …, 2008 - Elsevier
The kallikrein family (KLK) has been implicated in cancer and may be useful as tumor
markers. Here, we compared the 15 KLK genes' expression in malignant and normal breast …

[HTML][HTML] Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues

GM Yousef, A Chang, EP Diamandis - Journal of Biological Chemistry, 2000 - ASBMB
Kallikreins are a subgroup of serine proteases and these proteolytic enzymes have diverse
physiological functions in many tissues. Growing evidence suggests that many kallikreins …

[HTML][HTML] Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status

F Fritzsche, T Gansukh, CA Borgono… - British journal of …, 2006 - nature.com
Abstract Human kallikrein 14 (KLK14) is a steroid hormone-regulated member of the tissue
kallikrein family of serine proteases, for which a prognostic and diagnostic value in breast …

Human Kallikrein Gene 5 (KLK5) Expression by Quantitative PCR: An Independent Indicator of Poor Prognosis in Breast Cancer

GM Yousef, A Scorilas, LG Kyriakopoulou… - Clinical …, 2002 - academic.oup.com
Background: KLK5 is a newly discovered human kallikrein gene. Many kallikrein genes
have been found to be differentially expressed in various malignancies, and prostate …

[HTML][HTML] Kallikrein gene downregulation in breast cancer

GM Yousef, GM Yacoub, ME Polymeris… - British journal of …, 2004 - nature.com
Recent evidence suggests that many members of the human kallikrein gene family are
differentially regulated in breast cancer and other endocrine-related malignancies. In this …

The Prognostic Value of the Human Kallikrein Gene 9 (KLK9) in Breast Cancer

GM Yousef, A Scorilas, T Nakamura… - Breast cancer research …, 2003 - Springer
Background. Many members of the human kallikrein gene family were found to be
differentially expressed in various malignancies and some of them are useful …

Kallikrein 11 down-regulation in breast carcinoma: correlation with prognostic parameters

T Ozturk, EZ Kain, MB Tuzuner, A Diren, S Batur… - in vivo, 2021 - iv.iiarjournals.org
Background: Expression of kallikrein-11 (KLK11) has been found to be related to the
prognosis of various human cancer types but its physiological functions in the steps of breast …

Clinicopathologic and biological significance of kallikrein 6 overexpression in human gastric cancer

H Nagahara, K Mimori, T Utsunomiya, GF Barnard… - Clinical cancer …, 2005 - AACR
Purpose: Human kallikrein genes (KLK) have been reported to be involved in human
malignancies and several KLK s are promising biomarkers of prostate, ovarian, testicular …