Expression of integrin-linked kinase is not a useful prognostic marker in resected hepatocellular cancer

P Intaraprasong, K Assi, DA Owen… - Anticancer …, 2007 - ar.iiarjournals.org
Background: Hepatocellular cancer (HCC) is one of the most common malignancies
worldwide, and is known to be associated with a poor prognosis. Unfortunately there are no …

[HTML][HTML] Integrin-linked kinase overexpression and its oncogenic role in promoting tumorigenicity of hepatocellular carcinoma

J Chan, FCF Ko, YS Yeung, IOL Ng, JWP Yam - PloS one, 2011 - journals.plos.org
Background Integrin-linked kinase (ILK) was first discovered as an integrin β1-subunit
binding protein. It localizes at the focal adhesions and is involved in cytoskeleton …

ILK overexpression in human hepatocellular carcinoma and liver cirrhosis correlates with activation of Akt

S Peroukides, V Bravou, J Varakis… - Oncology …, 2008 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common life-threatening malignancies in
the world. The molecular mechanisms leading to the development of HCC are complex and …

Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer

R Li, B Liu, H Yin, W Sun, J Yin, Q Su - Journal of molecular histology, 2013 - Springer
Abstract Integrin-linked kinase (ILK), an intracellular serine-threonine kinase, has been
reported to be overexpressed in multiple types of human malignancies, including colorectal …

High expression of integrin-linked kinase predicts aggressiveness and poor prognosis in patients with gastric cancer

X Gu, X Xing, W Yang, J Hu, D Dai - Acta Histochemica, 2014 - Elsevier
Abstract Integrin-linked kinase (ILK), an intracellular serine/threonine protein kinase, has
been reported to be highly expressed in many human malignancies, including gastric …

Expression of integrin-linked kinase is increased in differentiated cells

M Haase, CC Gmach, I Eke… - … of Histochemistry & …, 2008 - journals.sagepub.com
Integrin-linked kinase (ILK), a mediator of β integrin signals, has emerged as a therapeutic
target in malignant tumors. Because malignant transformation is accompanied by …

[HTML][HTML] Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer

I Takanami - BMC cancer, 2005 - Springer
Background Integrin-linked kinase (ILK) promotes tumor growth and invasion. Increased ILK
expression is correlated with progression of several tumor types, but the expression of ILK …

Expression of integrin-linked kinase is closely correlated with invasion and metastasis of gastric carcinoma

R Ito, N Oue, X Zhu, K Yoshida, H Nakayama… - Virchows Archiv, 2003 - Springer
Integrin-linked kinase (ILK), a serine/threonine protein kinase, implicates in cellular control
of cell-matrix interactions and cell proliferation that is associated with a highly invasive …

[HTML][HTML] Integrin linked kinase (ILK) and its role in liver pathobiology

N Martucci, GK Michalopoulos, WM Mars - Gene Expression, 2021 - ncbi.nlm.nih.gov
Integrin linked kinase (ILK) is a vital signaling protein ubiquitously expressed throughout the
body. It binds to intracellular integrins to help promote signaling related to cell adhesion …

Integrin-linked kinase (ILK) expression in human colon cancer

V Bravou, G Klironomos, E Papadaki… - British journal of …, 2003 - nature.com
We studied ILK expression in 84 human colorectal tumours (four adenomas and 80
carcinomas) by immunohistochemistry in order to assess whether ILK is involved in the …