Environmental oestrogens and breast cancer: evidence for combined involvement of dietary, household and cosmetic xenoestrogens

PD Darbre, AK Charles - Anticancer Research, 2010 - ar.iiarjournals.org
Many environmental compounds with oestrogenic activity are measurable in the human
breast and oestrogen is a known factor in breast cancer development. Exposure to …

Environmental oestrogens, cosmetics and breast cancer

PD Darbre - Best practice & research clinical endocrinology & …, 2006 - Elsevier
The established role of oestrogen in the development and progression of breast cancer
raises questions concerning a potential contribution from the many chemicals in the …

Environmental oestrogens and breast cancer: long-term low-dose effects of mixtures of various chemical combinations

PD Darbre, MF Fernandez - J Epidemiol Community Health, 2013 - jech.bmj.com
The incidence of breast cancer has risen worldwide to unprecedented levels in recent
decades, making it now the major cancer of women in many parts of the world. 1 Although …

Medical hypothesis: xenoestrogens as preventable causes of breast cancer.

DL Davis, HL Bradlow, M Wolff… - Environmental …, 1993 - ehp.niehs.nih.gov
Changes in documented risk factors for breast cancer and rates of screening cannot
completely explain recent increases in incidence or mortality. Established risk factors for …

The role of xenoestrogenic compounds in the development of breast cancer

S Safe, S Papineni - Trends in pharmacological sciences, 2006 - cell.com
Lifetime exposure to endogenous steroidal estrogens is an established risk factor for breast
cancer, and exposures to other estrogenic and antiestrogenic compounds might also modify …

Interactions between hormones and chemicals in breast cancer

SH Safe - Annual review of pharmacology and toxicology, 1998 - annualreviews.org
▪ Abstract Development of breast cancer in women is dependent on diverse factors,
including genetic predisposition, exposure to both exogenous and endogenous chemicals …

Endocrine disrupters and human health: could oestrogenic chemicals in body care cosmetics adversely affect breast cancer incidence in women? A review of …

PW Harvey, P Darbre - Journal of Applied Toxicology: An …, 2004 - Wiley Online Library
Harrison (2001) and Sharpe and Irvine (2004) have recently summarized the hypotheses
and status of evidence implicating endocrine disruption and adverse impacts on human …

Environmental estrogens and breast cancer risk

NE Davidson - Current opinion in oncology, 1998 - journals.lww.com
Controversy exists over the role that environmental estrogens, such as pesticides or
polychlorinated biphenyls (PCBs), might play as risk factors for breast cancer. Several …

Is there an association between exposure to environmental estrogens and breast cancer?

SH Safe - Environmental Health Perspectives, 1997 - ehp.niehs.nih.gov
It was initially reported that levels of polychlorinated biphenyls (PCBs) or p, p'-DDE were
elevated in breast cancer patients (serum or tissue) versus controls. These results, coupled …

Can environmental estrogens cause breast cancer?

D Lee Davis, HL Bradlow - Scientific American, 1995 - JSTOR
Early Thinking: reast cancer, like other malignan-cies, arises when a cell escapes the usual
restraints on replication and multiplies out of control. This escape is now believed to require …