Background/Aim: Treatment of colorectal cancer (CRC) does not reflect immune interactions
between tumours and macro-organisms. Serpin B9 is known as an inhibitor of Granzyme B …

Serpin B5 is a candidate tumour suppressor, but its oncogenic activity has also been
reported. Its function may be affected by protein interactions. The aim of this study was to …

Serine proteinase inhibitor B9 (serpin B9) is a member of the serine protease inhibitor
superfamily, which is widely found in animals, plants and microorganisms. Serpin B9 has …

Serpina family A member 4 (SERPINA4), also known as kallistatin, exerts important effects in
inhibiting tumor growth and angiogenesis in many malignancies. However, the precise role …

Abstract Background Serpin Peptidase Inhibitor 1 (SERPINE1) promotes cancer progression
by making it easier for cancer cells to spread to surrounding normal tissue. We expect to …

Background Colon cancer (CC) is a prevalent malignant tumor that affects the colon in the
gastrointestinal tract. Its aggressive nature, strong invasiveness, and rapid progression …

Proteases facilitate a number of steps in cancer progression. The serine protease inhibitors
(serpins) are a protein superfamily with inhibitory activity against proteases. One of these …

Background The change of immune cell infiltration essentially influences the process of
colorectal cancer development. The infiltration of immune cells can be regulated by a variety …

Background: The aberrant expression of serpin family E member 1 (SERPINE1) is
associated with carcinogenesis. This study assessed the alteration of SERPINE1 expression …

This study aimed to investigate the role of SERPINB5 in colorectal cancer (CRC). We
established knockdown and overexpression models of SERPINB5 in CRC cells and …