Phase II study of preoperative chemoradiotherapy with S-1 plus oxaliplatin for locally advanced rectal cancer (PerSeUS-RC01)

N Matsuhashi, T Takahashi, C Tanaka… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: We report the end results of a study evaluating the safety and efficacy of
preoperative chemoradiotherapy with S-1 plus oxaliplatin. Patients and Methods: Eligible …

A multicenter phase II study of preoperative chemoradiotherapy with S-1 plus oxaliplatin for locally advanced rectal cancer (SHOGUN trial)

S Matsusaka, S Ishihara, K Kondo, H Horie… - Radiotherapy and …, 2015 - Elsevier
Purpose This study was designed to evaluate the safety and efficacy of adding oxaliplatin to
preoperative chemoradiotherapy (CRT) with S-1 in patients with locally advanced rectal …

Long-term results of a multicenter phase II study of preoperative chemoradiotherapy with S-1 plus oxaliplatin for locally advanced rectal cancer (JACCRO CC-04 …

K Kondo, S Matsusaka, S Ishihara, H Horie… - Radiotherapy and …, 2019 - Elsevier
Purpose The study was designed to evaluate the safety and efficacy of adding oxaliplatin to
py (CRT) with S-1 in patients with locally advanced rectal carcinoma (LARC). We report here …

Efficacy and safety of preoperative chemoradiotherapy with S-1 for advanced rectal cancer: a phase II study

M Ushigome, K Funahashi, T Kaneko… - reports of practical …, 2023 - journals.viamedica.pl
Background: Preoperative chemoradiotherapy (CRT) for patients with rectal cancer is not yet
established in Japan. We aimed to evaluate the efficacy and safety of preoperative CRT with …

Efficacy and tolerability of preoperative chemoradiotherapy with S-1 alone for locally advanced rectal cancer

N Imano, Y Murakami, K Kubo… - Journal of Radiation …, 2021 - academic.oup.com
Preoperative chemoradiotherapy with capecitabine or 5-fluorouracil is a standard treatment
for locally advanced rectal cancer (LARC). S-1, a prodrug of 5-fluorouracil, is a candidate for …

Phase I study of preoperative chemoradiation with s-1 and oxaliplatin in patients with locally advanced resectable rectal cancer

YS Hong, JL Lee, JH Park, JH Kim, SN Yoon… - International Journal of …, 2011 - Elsevier
PURPOSE: To perform a Phase I study of preoperative chemoradiation (CRT) with S-1, a
novel oral fluoropyrimidine, plus oxaliplatin in patients with locally advanced rectal cancer …

[HTML][HTML] Short‑term outcomes of preoperative chemoradiotherapy with S‑1 for locally advanced rectal cancer

M Hiraki, T Tanaka, Y Hiraki… - Molecular and …, 2021 - spandidos-publications.com
The purpose of the present study was to evaluate the short‑term results of preoperative
chemoradiation therapy with S‑1 for locally advanced rectal cancer. A total of 32 patients …

A multicenter phase II study of preoperative concurrent chemoradiotherapy with S-1 plus irinotecan for locally advanced rectal cancer: SAMRAI-2

M Noda, T Sato, K Hayakawa, N Tomita… - Annals of …, 2016 - annalsofoncology.org
Background We previously conducted a phase I study of preoperative concurrent
chemoradiotherapy combining S-1 and irinotecan with radiotherapy of the lesser pelvis in …

A phase I trial of preoperative S-1 in combination with oxaliplatin and pelvic radiation for lower rectal cancer with T4 and lateral pelvic lymph node metastasis

M Ohue, T Hamaguchi, Y Ito, D Sakai, S Noura… - International Journal of …, 2015 - Springer
Background The purpose of this phase I study of the dose escalation of oxaliplatin in
combination with oral S-1 and pelvic radiation preoperatively for poor-risk lower rectal …

A multicenter phase II trial of preoperative chemoradiotherapy with S-1 plus oxaliplatin and bevacizumab for locally advanced rectal cancer

J Higashijima, T Tokunaga, T Yoshimoto, S Eto… - International Journal of …, 2021 - Springer
Background We clarified the safety and efficacy of preoperative chemoradiotherapy for
locally advanced rectal cancer using a multidrug regimen (S-1+ oxaliplatin+ bevacizumab) …