Effect of inhibition of the ROCK isoform on RT2 malignant glioma cells
N Inaba, S Ishizawa, M Kimura, K Fujioka… - Anticancer …, 2010 - ar.iiarjournals.org
Background: Malignant glioma is one of the most intractable diseases in the human body.
Rho-kinase (ROCK) is overexpressed and has been proposed as the main cause for the …
Rho-kinase (ROCK) is overexpressed and has been proposed as the main cause for the …
Knockdown of Rho-associated protein kinase 1 suppresses proliferation and invasion of glioma cells
P Zhang, Y Lu, XY Liu, YH Zhou - Tumor Biology, 2015 - Springer
Rho-associated protein kinase 1 (ROCK1), a serine/threonine protein kinase, affects cell
invasion and migration by changing the status of the cytoskeleton. In recent years, ROCK1 …
invasion and migration by changing the status of the cytoskeleton. In recent years, ROCK1 …
[HTML][HTML] Serum ROCK1 mRNA is of great diagnostic value for glioma patients
Y Liu, J Zhang, D Wang, X Yang - Medicine, 2019 - journals.lww.com
Serum ROCK1 mRNA is of great diagnostic value for glioma pat... : Medicine Serum ROCK1
mRNA is of great diagnostic value for glioma patients : Medicine Log in or Register Get new …
mRNA is of great diagnostic value for glioma patients : Medicine Log in or Register Get new …
[HTML][HTML] Overexpression of ROCK1 and ROCK2 inhibits human laryngeal squamous cell carcinoma
J Zhang, X He, Y Ma, Y Liu, H Shi… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Rho-associated coiled-coil containing protein kinase (ROCK) over-expression has been
implicated in the progression of many tumor types. The aim of this study was to explore the …
implicated in the progression of many tumor types. The aim of this study was to explore the …
Upregulation of ROCK2 in gastric cancer cell promotes tumor cell proliferation, metastasis and invasion
M Li, J Ke, Q Wang, H Qian, L Yang, X Zhang… - Clinical and …, 2017 - Springer
Rho-associated coiled-coil-containing protein kinase 2 (ROCK2) has been known as an
effector for the small GTPase Rho and plays an important role in tumor progression and …
effector for the small GTPase Rho and plays an important role in tumor progression and …
Overexpression of ROCK1 promotes cancer cell proliferation and is associated with poor prognosis in human urothelial bladder cancer
Y Mei, Y Wu, L Ma, H Zhang, L Li, F Wang - Mammalian Genome, 2021 - Springer
Rho-associated protein kinase 1 (ROCK1) has been reported to be overexpressed in many
types of tumors, but its role in urothelial bladder cancer is poorly understood. The study aims …
types of tumors, but its role in urothelial bladder cancer is poorly understood. The study aims …
[HTML][HTML] The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells
J Wang, XH Liu, ZJ Yang, B Xie, YS Zhong - BMC cancer, 2014 - Springer
Abstract Background Retinoblastoma (Rb) is the most common intraocular tumor in
childhood worldwide. It is a deadly pediatric eye cancer. The main cause of death in Rb …
childhood worldwide. It is a deadly pediatric eye cancer. The main cause of death in Rb …
[HTML][HTML] Novel insights into the roles of Rho kinase in cancer
L Wei, M Surma, S Shi, N Lambert-Cheatham… - Archivum immunologiae …, 2016 - Springer
Rho-associated coiled-coil kinase (ROCK) is a major downstream effector of the small
GTPase RhoA. The ROCK family, consisting of ROCK1 and ROCK2, plays a central role in …
GTPase RhoA. The ROCK family, consisting of ROCK1 and ROCK2, plays a central role in …
Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma
M Nakajima, K Hayashi, Y Egi, K Katayama… - Cancer chemotherapy …, 2003 - Springer
Purpose Rho-associated coiled-coil-forming protein kinase (ROCK) is pivotally involved in
invasion by tumor cells and their evolution to metastasis. We have developed a novel …
invasion by tumor cells and their evolution to metastasis. We have developed a novel …
ROCK1 as a potential therapeutic target in osteosarcoma
Osteosarcoma is the most common primary malignancy of bone. Patients with localized
disease are routinely treated with surgery and chemotherapy. Unfortunately, many of these …
disease are routinely treated with surgery and chemotherapy. Unfortunately, many of these …