Background/Aim: While aberrant expression of cyclin-dependent kinase-4 (CDK4) has been
found in squamous cell carcinoma of the head and neck (SCCHN), the associations …

Oral squamous cell carcinoma (OSCC) is a major global health problem with a relatively low‐
moderate 5‐year survival rate. OSCC is often preceded by lesions and conditions known as …

Background The objective of this study was to investigate the role and molecular mechanism
of cyclin‐dependent kinase 5 (CDK5) in regulating the growth of tongue squamous cell …

Increased expression of cyclin-dependent kinase 7 (CDK7), an ubiquitous kinase
associated with cell cycle and transcription, contributes to human tumourigenesis and …

Background: Cyclin dependent kinase-4 (CDK4) encoded by CDK gene, is a heterodimer
protein of cell cycle in G1-S transition. This study aimed to characterize the CDK4 …

Cyclins and cyclin‐dependent kinases (CDKs) play key roles in cell cycle regulation, a
process of which dysregulation can lead to uncontrolled cell growth and hence to cancer …

Objectives: To evaluate the clinical significance of cyclin-dependent kinase 1 (CDK1) in 77
oral squamous cell carcinomas (OSCC) using immunohistochemical methods. Study …

The aim of the current study was to investigate the expression of cyclin‑dependent kinase 3
(CDK3) in human nasopharyngeal carcinoma (NPC) and to evaluate its association with the …

Maintenance of oral epithelial homeostasis requires a fine balance between cell
proliferation and differentiation. However, the molecular mechanisms that couple these …

Data mining in the public domain demonstrates that cyclin-dependent kinase 4 (CDK4) is
highly expressed in nasopharyngeal carcinomas (NPC). Associated with cyclin-D, CDK4 …