Significant contribution of interleukin-18 genotypes to lung cancer risk in Taiwanese

MF Wu, LH Chen, NY Hsia, YC Shen… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: The elevated expression of interleukin-18 (IL-18) among lung cancer
patients raised our curiosity to examine the role of IL-18 genotypes in lung cancer. Materials …

The interleukin-18 gene promoter -607 A/C polymorphism contributes to non-small-cell lung cancer risk in a Chinese population

Y Jia, A Zang, S Jiao, S Chen, F Yan - OncoTargets and therapy, 2016 - Taylor & Francis
The purpose of the present study was to determine the relationship between interleukin-18
(IL-18)-607 A/C polymorphism and the risk of non-small-cell lung cancer (NSCLC) and its …

Interleukin-18 promoter polymorphism is associated with lung cancer: a case-control study

A Farjadfar, Z Mojtahedi, MA Ghayumi, N Erfani… - Acta …, 2009 - Taylor & Francis
Background. Interleukin-18 (IL-18) is a multifunctional cytokine that augments IFN-γ
production and affects tumor immune response. In the present case-control study, we tested …

Significant association of interleukin-16 genetic variations to Taiwanese lung cancer

MF Wu, YC Wang, TC Shen, WS Chang, HT Li… - in vivo, 2020 - iv.iiarjournals.org
Background/Aim: Interleukin-16 has been reported to exhibit tumoricidal effects, however,
the contribution of IL-16 genotypes to lung cancer is still largely unrevealed. This study …

[PDF][PDF] Association between IL18-607C/A and-137G/C polymorphisms and susceptibility to non-small cell lung cancer in a Chinese population

WY Gan, HM Li, YG Zhang, CM Li, Y Wang - Genet Mol Res, 2016 - geneticsmr.com
Lung cancer is one of the main causes of cancer-related mortality in males and females
worldwide. A pleiotropic effect has been observed in the interleukin 18 gene (IL18); its …

The contribution of interleukin-12 genetic variations to Taiwanese lung cancer

MF Wu, YC Wang, HT Li, WC Chen, CH Liao… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Lung cancer is the leading cause of cancer-related death and a better
marker for advanced personalized therapeutic approaches, such as immunotherapies, is in …

Interleukin-17A and-17F genes polymorphisms in lung cancer

W Kaabachi, A ben Amor, S Kaabachi, A Rafrafi… - Cytokine, 2014 - Elsevier
Abstract Interleukin-17 (IL-17) is a proinflammatory cytokines produced by T helper 17
(Th17) cells, which plays an important role in both innate and adaptive immune systems …

Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk in Taiwan males and smokers

TC Hsia, WS Chang, SJ Liang, WC Chen… - Anticancer …, 2014 - ar.iiarjournals.org
Interleukin-10 (IL-10) is an immunosuppressive cytokine involved in carcinogenesis via
immune escape. The present study aimed at evaluating the contribution of IL-10 promoter A …

Interleukin 17A genetic variations and susceptibility to non‐small cell lung cancer

QY Ma, J Chen, SH Wang, N Wu, ZH Hao, XF Chen - APMIS, 2015 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related death, in which non‐small cell lung
cancer (NSCLC) is the most common type. Evidence have shown that interleukin 17 (IL‐17) …

Genetic polymorphisms and plasma levels of interleukin-22 contribute to the development of nonsmall cell lung cancer

F Liu, X Pan, L Zhou, J Zhou, B Chen, J Shi… - DNA and Cell …, 2014 - liebertpub.com
Interleukin (IL)-22, a relatively new member of the IL-10 family, has been implicated in
inflammation and tumorigenesis. The aim of this study was to identify genetic polymorphisms …