Background: Thymidine kinase 1 (TK1) is a biomarker elevated in several malignancies,
including lung cancer. Up-regulation of TK1 is an early event in carcinogenesis and …

Abstract Thymidine kinase 1 (TK1) is a pyrimidine metabolic pathway enzyme involved in
salvage DNA synthesis and thus, a cell cycle-dependent marker. We have developed anti …

Introduction Thymidine kinase 1 (TK1) is a metabolic enzyme involved in DNA synthesis.
Most standard treatment protocols for lung cancer (LC) include cytotoxic agents, which are …

Abstract Thymidine Kinase 1 (TK1) is traditionally a serum biomarker which is elevated in
the early stages of malignancies. TK1 is a DNA repair enzyme which is typically associated …

Background: Whether thymidine kinase (TK) is considered a new diagnostic biomarker in
lung cancer depends on it being superior to or adding further information to already …

Thymidine kinase 1 (TK1) is a key enzyme in DNA precursor synthesis. It is upregulated
during the S phase of the cell cycle and its presence in cells is an indicator of active cell …

Abstract Thymidine kinase 1 (TK1) is a key enzyme involved in the synthesis of DNA
precursors and thus, cell proliferation-dependent. Antibodies against TK1 have provided …

Background Lung, breast, and colorectal malignancies are the leading cause of cancer-
related deaths in the world causing over 2.8 million cancer-related deaths yearly. Despite …

Patients with esophageal cancer are often diagnosed at advanced stages, leading to poor
prognosis. Biomarkers are needed to enable earlier detection as well as to aid in the …

Context: TK1 found to be elevated biomarker in many solid cancers. Objectives: The study
aimed to assess the prognostic significance of a serum TK1 in patients with metastatic …