The role of histone deacetylase inhibitors in uveal melanoma: current evidence
MM Moschos, M Dettoraki, S Androudi… - Anticancer …, 2018 - ar.iiarjournals.org
Uveal melanoma is the most common intraocular malignancy in adults, representing
approximately 3% of all melanoma cases. Despite progress in chemotherapy, radiation and …
approximately 3% of all melanoma cases. Despite progress in chemotherapy, radiation and …
[HTML][HTML] Histone Deacetylase (HDAC)-1,-2,-4, and-6 in Uveal Melanomas: Associations with Clinicopathological Parameters and Patients' Survival
G Levidou, P Gajdzis, N Cassoux, P Donizy… - Cancers, 2021 - mdpi.com
Simple Summary Histone Deacetylases (HDACs) have been reportedly associated with
tumor development and progression in several types of human malignancy, being currently …
tumor development and progression in several types of human malignancy, being currently …
Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma
S Landreville, OA Agapova, KA Matatall, ZT Kneass… - Clinical cancer …, 2012 - AACR
Purpose: Metastasis is responsible for the death of most cancer patients, yet few therapeutic
agents are available which specifically target the molecular events that lead to metastasis …
agents are available which specifically target the molecular events that lead to metastasis …
Tumour expression of histone deacetylases in uveal melanoma
Purpose: To determine the expression of histone deacetylase enzymes in uveal melanoma
tumour cells. Procedures: This is an observational immunohistochemical study of 16 …
tumour cells. Procedures: This is an observational immunohistochemical study of 16 …
Targeting histone deacetylases in malignant melanoma: a future therapeutic agent or just great expectations?
N Garmpis, C Damaskos, A Garmpi… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Malignant melanoma is the most aggressive type of skin cancer, with
increasing frequency and mortality. Melanoma is characterized by rapid proliferation and …
increasing frequency and mortality. Melanoma is characterized by rapid proliferation and …
Identification of histone deacetylase inhibitors with (arylidene) aminoxy scaffold active in uveal melanoma cell lines
Uveal melanoma (UM) represents an aggressive type of cancer and currently, there is no
effective treatment for this metastatic disease. In the last years, histone deacetylase …
effective treatment for this metastatic disease. In the last years, histone deacetylase …
[HTML][HTML] Uveal melanoma cell line proliferation is inhibited by ricolinostat, a histone deacetylase inhibitor
H Sundaramurthi, S García-Mulero, V Tonelotto… - Cancers, 2022 - mdpi.com
Simple Summary Uveal melanoma (UM) is the most common adult eye cancer. UM
originates in the iris, ciliary body or choroid (collectively known as the uvea), in the middle …
originates in the iris, ciliary body or choroid (collectively known as the uvea), in the middle …
[HTML][HTML] Class III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanoma
W Dai, J Zhou, B Jin, J Pan - Scientific reports, 2016 - nature.com
Uveal melanoma (UM) is the most common intraocular malignancy in adults. Despite
improvements in surgical, radiation and chemotherapy treatments, the overall survival of UM …
improvements in surgical, radiation and chemotherapy treatments, the overall survival of UM …
[HTML][HTML] Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications
purpose. To characterize the molecular sequelae induced in retinoblastoma (Rb) cells by
histone deacetylase inhibitors (HDACIs). Hydroxamic acid-based HDACIs such as vorinostat …
histone deacetylase inhibitors (HDACIs). Hydroxamic acid-based HDACIs such as vorinostat …
[HTML][HTML] Histone deacetylase (HDAC) inhibitors: A promising weapon to tackle therapy resistance in melanoma
K Palamaris, M Moutafi, H Gakiopoulou… - International Journal of …, 2022 - mdpi.com
Melanoma is an aggressive malignant tumor, arising more commonly on the skin, while it
can also occur on mucosal surfaces and the uveal tract of the eye. In the context of the …
can also occur on mucosal surfaces and the uveal tract of the eye. In the context of the …
Related searches
- uveal melanomas histone deacetylase
- hdac inhibitor uveal melanoma
- hdac inhibitors histone deacetylase
- growth arrest uveal melanoma
- promising weapon histone deacetylase
- uveal melanomas clinicopathological parameters
- tumour expression histone deacetylases
- tumour expression uveal melanoma
- clinicopathological parameters histone deacetylase
- therapy resistance histone deacetylase
- malignant melanoma histone deacetylases