Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells

MLY Bangaru, S Chen, J Woodliff… - Anticancer research, 2010 - ar.iiarjournals.org
Medulloblastoma (MB) is the most common malignant brain tumor in children. Bcl-2 and
MMP-9 promote the pathogenesis and progression of MB. The expression of both bcl-2 and …

[HTML][HTML] Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo

SJ Lee, C Krauthauser, V Maduskuie, PT Fawcett… - BMC cancer, 2011 - Springer
Background Medulloblastoma is the most common brain tumor in children, and its prognosis
is worse than for many other common pediatric cancers. Survivors undergoing treatment …

Curcumin induces apoptosis in human neuroblastoma cells via inhibition of NFκB

C Freudlsperger, J Greten, U Schumacher - Anticancer research, 2008 - ar.iiarjournals.org
Background: Metastasised neuroblastoma is a largely incurable neoplasia in children over
one year of age using current treatment protocols. After dissemination to the bone, the …

[HTML][HTML] Curcumin suppresses cell proliferation through inhibition of the Wnt/β-catenin signaling pathway in medulloblastoma

M He, Y Li, L Zhang, L Li, Y Shen, L Lin… - Oncology …, 2014 - spandidos-publications.com
Recently, the survival rate of medulloblastoma patients has greatly improved; yet, patients
undergoing current treatment regimes suffer from serious therapy-related side-effects. The …

Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation

P Picone, D Nuzzo, L Caruana, E Messina… - Free radical …, 2014 - Taylor & Francis
Neuroblastoma (NB) is one of the most frequent extracranial solid tumors in children. It
accounts for 8–10% of all childhood cancer deaths, and there is a need for development of …

Paraptosis in human glioblastoma cell line induced by curcumin

M Garrido-Armas, JC Corona, ML Escobar, L Torres… - Toxicology In Vitro, 2018 - Elsevier
Curcumin is a polyphenol compound extracted from Curcuma longa plant, is a molecule with
pleiotropic effects that suppresses transformation, proliferation and metastasis of malignant …

[HTML][HTML] Curcumin-mediated induction of apoptosis in human glioma CHME cells

Y Zhang, L Tu, X Zhou, B Li - Medical science monitor basic …, 2018 - ncbi.nlm.nih.gov
Background Curcumin has clear anti-tumor activity in various carcinomas. It regulates
various signaling pathways like Wnt/β-catenin and JAK2/STAT3, which play vital roles in cell …

Curcumin blocks brain tumor formation

S Purkayastha, A Berliner, SS Fernando… - Brain research, 2009 - Elsevier
Turmeric, an essential ingredient of culinary preparations of Southeast Asia, contains a
major polyphenolic compound, named curcumin or diferuloylmethane, which eliminates …

Investigating the therapeutic role and molecular biology of curcumin as a treatment for glioblastoma

GA Rodriguez, AH Shah, ZC Gersey… - … in medical oncology, 2016 - journals.sagepub.com
Objectives: Despite the aggressive standard of care for patients with glioblastoma
multiforme, survival rates typically do not exceed 2 years. Therefore, current research is …

Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas

S Curic, Y Wu, B Shan, C Schaaf, D Utpadel… - Journal of neuro …, 2013 - Springer
Meningiomas, the most frequent benign intracranial and intraspinal types of tumors are
normally removed by surgery. Complications can occur when the tumor is critically localized …