Curcumin (diferuloylmethane) induces apoptosis and blocks migration of human medulloblastoma cells
MLY Bangaru, S Chen, J Woodliff… - Anticancer research, 2010 - ar.iiarjournals.org
Medulloblastoma (MB) is the most common malignant brain tumor in children. Bcl-2 and
MMP-9 promote the pathogenesis and progression of MB. The expression of both bcl-2 and …
MMP-9 promote the pathogenesis and progression of MB. The expression of both bcl-2 and …
[HTML][HTML] Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo
SJ Lee, C Krauthauser, V Maduskuie, PT Fawcett… - BMC cancer, 2011 - Springer
Background Medulloblastoma is the most common brain tumor in children, and its prognosis
is worse than for many other common pediatric cancers. Survivors undergoing treatment …
is worse than for many other common pediatric cancers. Survivors undergoing treatment …
Curcumin induces apoptosis in human neuroblastoma cells via inhibition of NFκB
C Freudlsperger, J Greten, U Schumacher - Anticancer research, 2008 - ar.iiarjournals.org
Background: Metastasised neuroblastoma is a largely incurable neoplasia in children over
one year of age using current treatment protocols. After dissemination to the bone, the …
one year of age using current treatment protocols. After dissemination to the bone, the …
[HTML][HTML] Curcumin suppresses cell proliferation through inhibition of the Wnt/β-catenin signaling pathway in medulloblastoma
M He, Y Li, L Zhang, L Li, Y Shen, L Lin… - Oncology …, 2014 - spandidos-publications.com
Recently, the survival rate of medulloblastoma patients has greatly improved; yet, patients
undergoing current treatment regimes suffer from serious therapy-related side-effects. The …
undergoing current treatment regimes suffer from serious therapy-related side-effects. The …
Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation
Neuroblastoma (NB) is one of the most frequent extracranial solid tumors in children. It
accounts for 8–10% of all childhood cancer deaths, and there is a need for development of …
accounts for 8–10% of all childhood cancer deaths, and there is a need for development of …
Paraptosis in human glioblastoma cell line induced by curcumin
Curcumin is a polyphenol compound extracted from Curcuma longa plant, is a molecule with
pleiotropic effects that suppresses transformation, proliferation and metastasis of malignant …
pleiotropic effects that suppresses transformation, proliferation and metastasis of malignant …
[HTML][HTML] Curcumin-mediated induction of apoptosis in human glioma CHME cells
Y Zhang, L Tu, X Zhou, B Li - Medical science monitor basic …, 2018 - ncbi.nlm.nih.gov
Background Curcumin has clear anti-tumor activity in various carcinomas. It regulates
various signaling pathways like Wnt/β-catenin and JAK2/STAT3, which play vital roles in cell …
various signaling pathways like Wnt/β-catenin and JAK2/STAT3, which play vital roles in cell …
Curcumin blocks brain tumor formation
S Purkayastha, A Berliner, SS Fernando… - Brain research, 2009 - Elsevier
Turmeric, an essential ingredient of culinary preparations of Southeast Asia, contains a
major polyphenolic compound, named curcumin or diferuloylmethane, which eliminates …
major polyphenolic compound, named curcumin or diferuloylmethane, which eliminates …
Investigating the therapeutic role and molecular biology of curcumin as a treatment for glioblastoma
Objectives: Despite the aggressive standard of care for patients with glioblastoma
multiforme, survival rates typically do not exceed 2 years. Therefore, current research is …
multiforme, survival rates typically do not exceed 2 years. Therefore, current research is …
Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas
Meningiomas, the most frequent benign intracranial and intraspinal types of tumors are
normally removed by surgery. Complications can occur when the tumor is critically localized …
normally removed by surgery. Complications can occur when the tumor is critically localized …