Contrast-enhanced Ultrasound Imaging of Antiangiogenic Tumor Therapy

LV Klotz, DA Clevert, S Scheckinger, S Strieth… - Anticancer …, 2015 - ar.iiarjournals.org
Background/Aim: Anti-angiogenic treatment is a promising strategy for cancer therapy and is
currently evaluated in clinical trials. The aim of the present study was to further investigate …

Contrast-enhanced ultrasound with perflubutane in the assessment of anti-angiogenic effects: early prediction of the anticancer activity of bevacizumab in a mouse …

R Watanabe, T Munemasa, M Matsumura - Ultrasound in Medicine & …, 2015 - Elsevier
To investigate the feasibility of contrast-enhanced ultrasound (CEUS) with perflubutane for
evaluating anti-angiogenic effects, we assessed the contrast enhancement of mice xenograft …

Quantitative contrast enhanced ultrasound and CT assessment of tumor response to antiangiogenic therapy in rats

RE Pollard, AR Broumas, ER Wisner, SV Vekich… - Ultrasound in medicine …, 2007 - Elsevier
Contrast-enhanced computed tomography (CECT) and contrast-enhanced destruction-
replenishment subharmonic ultrasound (CEDRSU) were used to quantify blood flow and …

Molecular ultrasound imaging using a targeted contrast agent for assessing early tumor response to antiangiogenic therapy

AG Sorace, R Saini, M Mahoney… - Journal of Ultrasound in …, 2012 - Wiley Online Library
Objectives Contrast‐enhanced ultrasound (US) and targeted microbubbles have been
shown to be advantageous for angiogenesis evaluation and disease staging in cancer. This …

Contrast-assisted destruction-replenishment ultrasound for the assessment of tumor microvasculature in a rat model

RE Pollard, AR Sadlowski, SH Bloch… - … in cancer research …, 2002 - journals.sagepub.com
Angiogenesis, the development of new blood vessels, is necessary for tumor growth. Anti-
angiogenic therapies have recently received attention as a possible cancer treatment. The …

[HTML][HTML] Ultrasound contrast-enhanced study as an imaging biomarker for anti-cancer drug treatment: preliminary study with paclitaxel in a xenograft mouse tumor …

HJ Lee, SI Hwang, J Byun, HY Kong, HS Jung… - …, 2017 - ncbi.nlm.nih.gov
Purpose The purpose of this study was to assess tumor angiogenesis using contrast-
enhanced ultrasonography (CEUS) of human prostate cancer cells (PC3) that were …

Clinical relevance of contrast-enhanced ultrasound in monitoring anti-angiogenic therapy of cancer: current status and perspectives

M Lamuraglia, SL Bridal, M Santin, G Izzi, O Rixe… - Critical reviews in …, 2010 - Elsevier
Angiogenesis regulation is one of the newest fronts in the fight against cancer. Anti-
angiogenic therapy is based on inhibiting factors required to solicit vessel formation thus …

Molecular profiling of angiogenesis with targeted ultrasound imaging: early assessment of antiangiogenic therapy effects

M Palmowski, J Huppert, G Ladewig, P Hauff… - Molecular cancer …, 2008 - AACR
Molecular ultrasound is capable of elucidating the expression of angiogenic markers in vivo.
However, the capability of the method for volumetric “multitarget quantification” and for the …

Antitumor effect of TNP‐470, an angiogenesis inhibitor, combined with ultrasound irradiation for human uterine sarcoma xenografts evaluated using contrast color …

M Emoto, K Tachibana, H Iwasaki… - Cancer …, 2007 - Wiley Online Library
Microvascular endothelial cells, which are recruited by tumors, have become an important
target in cancer therapy. This study firstly examined the antitumor effect of angiogenesis …

Vascular targeting tumor therapy: non-invasive contrast enhanced ultrasound for quantitative assessment of tumor microcirculation

M Dr. Eichhorn, L Klotz, S Luedemann… - Cancer biology & …, 2010 - Taylor & Francis
The aim of the study was to quantitatively assess tumor microcirculation upon vascular
targeting tumor therapy by non-destructive contrast enhanced ultrasonography (CEUS) and …