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EBV rta-induced IL-6 promotes migration of bystander tumor cells through IL-6R/JAK/STAT3 pathway in vitro

KL Tung, YT Wu, C Liu, SC Lin, CH Wu… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Rta, a transactivator of Epstein-Barr virus, is associated with progression of
nasopharyngel carcinoma (NPC); however, its mechanism of contribution to the …
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[HTML][HTML] Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells

G Zhang, CM Tsang, W Deng, YL Yip, VWY Lui… - PloS one, 2013 - journals.plos.org
Nasopharyngeal carcinoma (NPC) is etiologically associated with Epstein-Barr virus (EBV)
infection. However, the exact role of EBV in NPC pathogenesis remains elusive. Activation of …
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STAT3 activation contributes directly to Epstein‐Barr virus–mediated invasiveness of nasopharyngeal cancer cells in vitro

VWY Lui, EYL Wong, Y Ho, B Hong… - … journal of cancer, 2009 - Wiley Online Library
Nasopharyngeal cancer (NPC) is an Epstein‐Barr virus (EBV)‐associated head and neck
cancer prevalent in Asia. Although with reasons not fully understood, the intrinsic …
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Epstein-Barr virus Rta promotes invasion of bystander tumor cells through paracrine of matrix metalloproteinase 9

YY Lan, FH Chang, JH Tsai, Y Chang - Biochemical and biophysical …, 2018 - Elsevier
Clinical studies suggest a positive association between malignant progression of
nasopharyngeal carcinoma (NPC) and Rta, a transcription factor of Epstein-Barr virus (EBV) …
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[HTML] aacrjournals.org

Epstein–Barr virus-induced VEGF and GM-CSF drive nasopharyngeal carcinoma metastasis via recruitment and activation of macrophages

D Huang, SJ Song, ZZ Wu, W Wu, XY Cui, JN Chen… - Cancer research, 2017 - AACR
Chronic inflammation induced by persistent microbial infection plays an essential role in
tumor progression. Although it is well documented that Epstein–Barr virus (EBV) infection is …
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Epstein–Barr Virus miRNA BART2-5p Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing RND3

C Jiang, L Li, YQ Xiang, ML Lung, T Zeng, J Lu… - Cancer research, 2020 - AACR
Nasopharyngeal carcinoma is an Epstein–Barr virus (EBV)-related malignancy. Recently,
we found that the EBV-encoded miRNA BART2-5p was increased in the serum of patients …
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Epigallocatechin-3-gallate interferes with EBV-encoding AP-1 signal transduction pathway

Y Zhao, H Wang, XR Zhao, FJ Luo… - Zhonghua Zhong liu za …, 2004 - europepmc.org
Objective To elucidate the interference effect of Epigallocatechin-3-Gallate (EGCG) on
targets of Activator Protein-1 (AP-1) signal transduction pathway activated by EB virus …
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[HTML] mdpi.com

[HTML][HTML] Epstein-Barr Virus Promotes Tumor Angiogenesis by Activating STIM1-Dependent Ca2+ Signaling in Nasopharyngeal Carcinoma

J Ye, J Wei, Y Luo, Y Deng, T Que, X Zhang, F Liu… - Pathogens, 2021 - mdpi.com
Epstein-Barr virus (EBV) promotes tumor angiogenesis in nasopharyngeal carcinoma (NPC)
by activating store-operated Ca2+ entry. Since such entry has been linked to stromal …
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Epstein-Barr virus-coded miR-BART13 promotes nasopharyngeal carcinoma cell growth and metastasis via targeting of the NKIRAS2/NF-κB pathway

YJ Xu, R Zhou, JF Zong, WS Lin, S Tong, QJ Guo, C Lin… - Cancer letters, 2019 - Elsevier
Based on analysis of Epstein-Barr virus (EBV) BART microRNA expression profiles, we
previously reported that EBV-encoded miR-BART13 is upregulated in nasopharyngeal …
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[HTML][HTML] Migration of gastric cancer is suppressed by recombinant Newcastle disease virus (rL-RVG) via regulating α7-nicotinic acetylcholine receptors/ERK-EMT

X Bu, A Zhang, Z Chen, X Zhang, R Zhang, C Yin… - BMC cancer, 2019 - Springer
Background Nicotinic acetylcholine receptors (nAChRs) have been reported to be
overexpressed in malignancies in humans and is associated with tumorigenesis and cell …
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