Frequent and Specific Involvement of Changes of the p16–RB Pathway in Esophageal Neuroendocrine Carcinoma
K Fujimasa, N Ohike, T Norose, T Isobe… - Anticancer …, 2019 - ar.iiarjournals.org
Aim: This study investigated the immunohistochemical expression of retinoblastoma (RB)
protein and p16 protein in 10 neuroendocrine carcinomas (NECs), in comparison to two …
protein and p16 protein in 10 neuroendocrine carcinomas (NECs), in comparison to two …
[HTML][HTML] p16 in highly malignant esophageal carcinomas: the correlation with clinicopathological factors and human papillomavirus infection
H Ishida, A Kasajima, F Fujishima, R Akaishi, S Ueki… - Virchows Archiv, 2021 - Springer
Abstract p16 is generally considered to be a surrogate maker of human papillomavirus
(HPV) infection and also a predictive marker of favorable clinical outcome of patients with …
(HPV) infection and also a predictive marker of favorable clinical outcome of patients with …
[HTML][HTML] Prognostic impact of p16 and p21 on gastroenteropancreatic neuroendocrine tumors
S Liu, Y Chang, J Ma, X Li, X Li, J Fan… - Oncology …, 2013 - spandidos-publications.com
Aberrant expression of the cell cycle kinase inhibitors, p16 and p21, has been associated
with poor prognosis in a number of human malignancies. These proteins may also be …
with poor prognosis in a number of human malignancies. These proteins may also be …
Differential retinoblastoma and p16INK4A protein expression in neuroendocrine tumors of the lung
H Dosaka‐Akita, PT Cagle, H Hiroumi, M Fujita… - Cancer, 2000 - Wiley Online Library
BACKGROUND Neuroendocrine neoplasms of the lung represent a wide spectrum of
phenotypically and biologically distinct entities. Their histopathologic diagnosis, which …
phenotypically and biologically distinct entities. Their histopathologic diagnosis, which …
Concomitant analysis of p16/INK4, cyclin D1, and retinoblastoma protein expression in esophageal squamous cell carcinoma.
T Nakamura, H Ide, R Eguchi, K Hayashi… - Hepato …, 2003 - europepmc.org
BACKGROUND/AIMS: Cyclin D1 expression is one of the important biologic factors and its
close association with p16/INK4 and retinoblastoma protein expression has been proven in …
close association with p16/INK4 and retinoblastoma protein expression has been proven in …
Alterations in the p16INK4a/Cyclin D1/RB Pathway in Gastrointestinal Tract Endocrine Tumors
AFY Li, ACH Li, SH Tsay, WY Li… - American journal of …, 2008 - academic.oup.com
A series of 76 cases of gastrointestinal tract endocrine tumors, including 21 poorly
differentiated endocrine carcinomas (PDECs, small cell carcinomas) and 55 well …
differentiated endocrine carcinomas (PDECs, small cell carcinomas) and 55 well …
Alterations of retinoblastoma protein and p16INK4 protein expression in extrahepatic bile duct carcinomas.
X Cui, AM Hui, X Li, YZ Shi, T Takayama… - Hepato …, 2000 - europepmc.org
Results Two (6%) extrahepatic bile duct carcinomas were pRb negative, 26 (76%) showed
pRb overexpression, and 6 (18%) demonstrated moderate expression. Twenty-two (65%) …
pRb overexpression, and 6 (18%) demonstrated moderate expression. Twenty-two (65%) …
Frequent inactivation of P16 and P15 expression in human esophageal squamous cell carcinoma detected by RT-PCR
LH Jiao, LD Wang, EP Xing, GYY Yang… - World Journal of …, 1998 - wjgnet.com
AIM: The cyclin-dependent kinase inhibitors p16 and p15 play important roles in the
regulation of the cell cycle, and have been found to have tumor suppressor roles in a variety …
regulation of the cell cycle, and have been found to have tumor suppressor roles in a variety …
Relationship between p16 and Rb protein expression in astrocytomas
Y Lin, C Huang, D Liu - Zhonghua Bing li xue za zhi= Chinese …, 1997 - europepmc.org
Objective p16 and Rb protein were examined in primary astrocytomas in order to study the
correlation between p16 and Rb proteins. Methods p16 and Rb pretoin were immunostained …
correlation between p16 and Rb proteins. Methods p16 and Rb pretoin were immunostained …
Clinicopathological significance of pRb2/p130 expression in squamous cell carcinoma of the esophagus
T Nozoe, D Korenaga, S Itoh, M Futatsugi… - Journal of cancer …, 2002 - Springer
Purpose. The aim of the current study was to find out the significance of the
immunohistochemical expression of pRb2/p130, which is a member of the retinoblastoma …
immunohistochemical expression of pRb2/p130, which is a member of the retinoblastoma …
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