Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung …

KC Wu, ST Yang, TC Hsia, JS Yang… - Anticancer …, 2012 - ar.iiarjournals.org
Metastasis is a major cause of death of patients with malignant tumors. Matrix
metalloproteinases (MMPs) are important for the migration and invasion of various types of …

Propofol reduces MMPs expression by inhibiting NF-κB activity in human MDA-MB-231 cells

Q Li, L Zhang, Y Han, Z Jiang, Q Wang - Biomedicine & Pharmacotherapy, 2012 - Elsevier
Propofol is a common clinical anesthesia agent which is now widely used in relieving pain of
patients with chronic cancer as an adjuvant therapy. In our study, we found another effect of …

GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells

Y Miao, Y Zhang, H Wan, L Chen, F Wang - Biomedicine & …, 2010 - Elsevier
Propofol (2, 6-diisopropylphenol), one of the most commonly used intravenous anaesthetic
agents during cancer resection surgery, has been reported to have the ability of influencing …

[HTML][HTML] Propofol suppresses proliferation, invasion and angiogenesis by down-regulating ERK-VEGF/MMP-9 signaling in Eca-109 esophageal squamous cell …

YB Xu, QH Du, MY Zhang, P Yun… - Eur Rev Med Pharmacol …, 2013 - europeanreview.org
BACKGROUND AND AIMS: Propofol (2, 6-diisopropylphenol), one of the most commonly
used intravenous anaesthetic agents during cancer resection surgery, has been reported to …

[HTML][HTML] Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372

H Sun, D Gao - BMc cancer, 2018 - Springer
Background Propofol, a commonly used intravenous anesthetic during cancer resection
surgery, has been found to exhibit tumor inhibitory effects in vitro and in vivo. The role of …

Propofol induces endoplasmic reticulum (ER) stress and apoptosis in lung cancer cell H460

WY Cui, Y Liu, YQ Zhu, T Song, QS Wang - Tumor Biology, 2014 - Springer
Propofol is one of the most commonly used intravenous anesthetic agents during cancer
resection surgery. It can influence proliferation, motility, and invasiveness of cancer cells in …

Propofol suppresses proliferation and metastasis of colorectal cancer cells by regulating miR-124-3p. 1/AKT3

Y Li, W Dong, H Yang, G Xiao - Biotechnology letters, 2020 - Springer
Background Propofol, an extensively used intravenous anesthetic agents during cancer
resection surgery, has been confirmed to execute anti-tumor effect on multiple cancers …

[HTML][HTML] Propofol suppresses the progression of non‑small cell lung cancer via downregulation of the miR‑21‑5p/MAPK10 axis

X Wu, X Li, G Xu - Oncology Reports, 2020 - spandidos-publications.com
Non‑small cell lung cancer (NSCLC) accounts for> 80% of lung cancer cases and is the
leading cause of cancer‑associated mortality worldwide. Propofol is an anesthetic drug …

Propofol inhibits pancreatic cancer proliferation and metastasis by up‐regulating miR‐328 and down‐regulating ADAM8

X Yu, Y Gao, F Zhang - Basic & Clinical Pharmacology & …, 2019 - Wiley Online Library
Propofol is commonly used for anaesthesia during surgery, and accumulating evidence has
demonstrated that propofol is associated with tumour suppression. For example, propofol …

[PDF][PDF] Propofol induces apoptosis of non-small cell lung cancer cells via ERK1/2-dependent upregulation of PUMA.

SG Xing, KJ Zhang, JH Qu, YD Ren… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Propofol is one of the most commonly used intravenous anesthetic agents
used in cancer resections, but the effect of propofol on non-small cell lung cancer (NSCLC) …