Background/Aim: Protein connexin 43 (Cx43), a part of intercellular gap junctions, is
frequently down-regulated in tumors. The aim of the study was to compare Cx43 expression …

The aim of this study was the assessment of expression and location of CX32 and CX43 in
colorectal adenomas and carcinomas as well as analysis of expression of these proteins in …

BACKGROUND: Colorectal cancer is one of the most common cancers worldwide and
leading cause of cancer related deaths. Connexins are integral membrane proteins that form …

Background: Gap junctional intercellular communication (GJIC) is a mechanism for direct
cell-to-cell signalling and is mediated by gap junctions, which consist of transmembrane …

This study was conducted to determine the level of expression and cellular localization of
connexin 26 (Cx26) and the expression of p53 in colorectal adenocarcinoma as well as their …

Abstract Background Connexin26 (Cx26) is one of the connexins (Cxs) family members
which form gap junction channels. Cx26 is considered to be a tumor suppressor gene …

Abstract Purpose: Connexin 26 (Cx26) is one of the gap junction–forming family members
classically considered to be tumor suppressors. However, recent studies show association …

Connexins (Cxs) are critical for normal tissue development, differentiation, and cell
proliferation. Normal expression and function of Cxs are considered to play a role in tumor …

Abstract Connexin 43 (Cx43) is an important gap junction protein in vertebrates, which has
been reported to function as a tumor suppressor in a number of organs. However, the …

This article is the first to show that loss of connexin43 (Cx43) expression in colorectal tumors
is correlated with significantly shorter relapse‐free and overall survival. Cx43 was further …