Towards a personalized approach in pancreatic cancer diagnostics through plasma amino acid analysis
J Tumas, I Baskirova, T Petrenas… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Body fluid biomarkers may provide means for early pancreatic cancer
diagnosis, patient stratification, application of personalized approaches and, finally …
diagnosis, patient stratification, application of personalized approaches and, finally …
Comprehensive mass spectrometry based metabolic profiling of blood plasma reveals potent discriminatory classifiers of pancreatic cancer
S Urayama, W Zou, K Brooks… - … in Mass Spectrometry …, 2010 - Wiley Online Library
Poor outcome of pancreatic cancer necessitates development of an early diagnostic method
to reduce mortality. No reliable early diagnostic test for pancreatic cancer detection has …
to reduce mortality. No reliable early diagnostic test for pancreatic cancer detection has …
[HTML][HTML] Evaluating metabolite-based biomarkers for early diagnosis of pancreatic cancer: a systematic review
G Perazzoli, OM García-Valdeavero, M Peña, J Prados… - Metabolites, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with five-year
survival rates around 10%. The only curative option remains complete surgical resection, but …
survival rates around 10%. The only curative option remains complete surgical resection, but …
Search for early pancreatic cancer blood biomarkers in five European prospective population biobanks using metabolomics
J Fest, LS Vijfhuizen, JJ Goeman, O Veth… - …, 2019 - academic.oup.com
Most patients with pancreatic cancer present with advanced disease and die within the first
year after diagnosis. Predictive biomarkers that signal the presence of pancreatic cancer in …
year after diagnosis. Predictive biomarkers that signal the presence of pancreatic cancer in …
Feasibility of identifying pancreatic cancer based on serum metabolomics
OF Bathe, R Shaykhutdinov, K Kopciuk… - … , biomarkers & prevention, 2011 - AACR
Background: We postulated that the abundance of various metabolites in blood would
facilitate the diagnosis of pancreatic and biliary lesions, which could potentially prevent …
facilitate the diagnosis of pancreatic and biliary lesions, which could potentially prevent …
[HTML][HTML] Metabolomic profile in pancreatic cancer patients: a consensus-based approach to identify highly discriminating metabolites
Purpose pancreatic adenocarcinoma is the fourth leading cause of cancer related deaths
due to its aggressive behavior and poor clinical outcome. There is a considerable variability …
due to its aggressive behavior and poor clinical outcome. There is a considerable variability …
A systematic review on metabolomics-based diagnostic biomarker discovery and validation in pancreatic cancer
Introduction Metabolomics is an emerging approach for early detection of cancer. Along with
the development of metabolomics, high-throughput technologies and statistical learning, the …
the development of metabolomics, high-throughput technologies and statistical learning, the …
[HTML][HTML] Tissue amino acid profiles are characteristic of tumor type, malignant phenotype, and tumor progression in pancreatic tumors
N Hiraoka, S Toue, C Okamoto, S Kikuchi, Y Ino… - Scientific Reports, 2019 - nature.com
Tissue amino acid profiles depend on the cell types and extracellular components that
constitute the tissue, and their functions and activities. We aimed to characterize the tissue …
constitute the tissue, and their functions and activities. We aimed to characterize the tissue …
Plasma metabolite biomarkers for the detection of pancreatic cancer
Patients with pancreatic cancer (PC) are usually diagnosed at late stages, when the disease
is nearly incurable. Sensitive and specific markers are critical for supporting diagnostic and …
is nearly incurable. Sensitive and specific markers are critical for supporting diagnostic and …
[HTML][HTML] Profiling the metabolic disorder and detection of colorectal cancer based on targeted amino acids metabolomics
Y Yang, Z Wang, X Li, J Lv, R Zhong, S Gao… - Journal of Translational …, 2023 - Springer
Background The morbidity of cancer keeps growing worldwide, and among that, the
colorectal cancer (CRC) has jumped to third. Existing early screening tests for CRC are …
colorectal cancer (CRC) has jumped to third. Existing early screening tests for CRC are …
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