Characterization of low molecular weight protein tyrosine phosphatase isoforms in human breast cancer epithelial cell lines

I Alho, L Costa, M Bicho, C Coelho - Anticancer Research, 2013 - ar.iiarjournals.org
Background: Low molecular weight protein tyrosine phosphatase (LMW-PTP) is a
polymorphic protein with two major isoforms whose role in tumorigenesis is currently …

Up-regulated expression of low molecular weight protein tyrosine phosphatases in different human cancers

F Malentacchi, R Marzocchini, S Gelmini… - Biochemical and …, 2005 - Elsevier
Protein tyrosine phosphorylation, mediated by the balanced action of tyrosine kinases and
phosphatases, contributes to the regulation of the growth, migration, and invasion of normal …

The expression of low molecular weight protein tyrosine phosphatase is up‐regulated in 1, 2‐dimethylhydrazine‐induced colon tumours in rats

R Marzocchini, F Malentacchi, M Biagini… - … journal of cancer, 2008 - Wiley Online Library
Recent studies have assessed the role of low molecular weight protein tyrosine
phosphatase (LMW‐PTP) in cell transformation and tumour onset and progression …

The role of low-molecular-weight protein tyrosine phosphatase (LMW-PTP ACP1) in oncogenesis

I Alho, L Costa, M Bicho, C Coelho - Tumor Biology, 2013 - Springer
Protein tyrosine phosphorylation is a crucial cellular event that is involved in the most
important processes of cellular metabolism. Low-molecular-weight protein tyrosine …

Low molecular weight protein tyrosine phosphatase: Multifaceted functions of an evolutionarily conserved enzyme

A Caselli, P Paoli, A Santi, C Mugnaioni, A Toti… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Originally identified as a low molecular weight acid phosphatase, LMW-PTP is actually a
protein tyrosine phosphatase that acts on many phosphotyrosine-containing cellular …

[HTML][HTML] Low molecular weight protein tyrosine phosphatase isoforms regulate breast cancer cells migration through a RhoA dependent mechanism

I Alho, L Costa, M Bicho, C Coelho - PloS one, 2013 - journals.plos.org
Low molecular weight protein tyrosine phosphatase (LMW-PTP) has been associated with
cell proliferation control through dephosphorylation and inactivation of growth factor …

Protein tyrosine phosphatases and breast cancer

G Freiss, F Vignon - Critical reviews in oncology/hematology, 2004 - Elsevier
Protein tyrosine phosphatases (PTPs) consist of a large family of related enzymes, including
the group of classical PTPs with its two main subgroups, the transmembrane receptor-type …

Low molecular weight protein tyrosine phosphatases: small, but smart

G Raugei, G Ramponi, P Chiarugi - Cellular and Molecular Life Sciences …, 2002 - Springer
Low molecular weight protein tyrosine phosphatases (LMW-PTPs) are a family of 18-kDa
enzymes involved in cell growth regulation. Despite very limited sequence similarity to the …

Expression of protein tyrosine phosphatase alpha (RPTPα) in human breast cancer correlates with low tumor grade, and inhibits tumor cell growth in vitro and in vivo

E Ardini, R Agresti, E Tagliabue, M Greco, P Aiello… - Oncogene, 2000 - nature.com
Tyrosine phosphorylation is controlled by a balance of tyrosine kinases (PTKs) and protein
tyrosine phosphatases (PTPs). Whereas the contribution of PTKs to breast tumorigenesis is …

Low molecular weight protein tyrosine phosphatase genetic polymorphism and susceptibility to cancer development

I Alho, MC Bicho, R Carvalho, AP Da Silva… - Cancer genetics and …, 2008 - Elsevier
Low molecular weight protein tyrosine phosphatases (LMW-PTPs) are a family of 18-kDa
enzymes involved in cell growth regulation. Human acid phosphatase 1 (ACP1) is …