MDS/AML del (11)(q14) share common morphological features despite different chromosomal breakpoints

I Dambruoso, R Invernizzi, M Boni… - Anticancer …, 2017 - ar.iiarjournals.org
In myelodysplatic syndromes and acute myeloid leukemia (MDS/AML) deletion of the 11q14
region is a rare chromosomal defect (incidence: 0.6-1.0%), included within the intermediate …

[CITATION][C] Deletion 9q as the sole karyotypic abnormality in myelocytic disorders: a new case of myelodysplastic syndrome and its prognostic implications in acute …

TSK Wan, ESK Ma, CCK Lam… - Cancer Genetics …, 2003 - cancergeneticsjournal.org
Acute myelocytic leukemia (AML) and myelodysplastic syndrome (MDS) share similar
cytogenetic aberrations; however, interstitial deletion of chromosome 9q (9q), one of the …

Duplication of chromosome 1 [dup (1)(q21q32)] as the sole cytogenetic abnormality in a patient previously treated for AML

DF Beach, BL Barnoski, H Aviv, V Patel, R Schwarting… - Cancer Genetics, 2012 - Elsevier
A nonrandom structural gain of 1q may be seen in myelodysplastic syndrome (MDS) and
acute myeloid leukemia (AML), and often it is due to an unbalanced translocation. Dup …

Therapy-related myelodysplastic syndrome/acute myeloid leukemia with del (7)(q22) in a patient with de novo AML

YG Kim, SY Cho, TS Park, SH Oh… - Annals of Clinical & …, 2011 - Assoc Clin Scientists
A 55-year-old Korean woman was initially diagnosed with acute myelomonocytic leukemia
(AML). After induction chemotherapy was performed using cytarabine, idarubicin, and G …

Del (9q) AML: clinical and cytological characteristics and prognostic implications

A Peniket, J Wainscoat, L Side, S Daly… - British journal of …, 2005 - Wiley Online Library
Del (9q) is a recurrent cytogenetic abnormality in acute myeloid leukaemia (AML). We report
an analysis of 81 patients with del (9q) as a diagnostic karyotypic abnormality entered into …

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11

M Lafage-Pochitaloff, B Gerby, V Baccini… - Blood …, 2022 - ashpublications.org
Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal
hematopoietic stem cell disorders characterized by ineffective hematopoiesis leading to …

Polymerase chain reaction-based diagnosis of del (5q) in acute myeloid leukemia and myelodysplastic syndrome identifies a minimal deletion interval

SK Horrigan, CA Westbrook, AH Kim, M Banerjee… - 1996 - ashpublications.org
Loss of all or part of the long arm of human chromosome 5 is a recurrent abnormality in
patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) …

Deletion of 16q11 is a recurrent cytogenetic aberration in acute myeloblastic leukemia during disease progression

K Yamamoto, K Nagata, A Kida… - Cancer genetics and …, 2001 - Elsevier
Abnormalities of chromosome 16 other than inv (16)(p13q22), t (16; 16)(p13; q22), and del
(16)(q22) have not been fully characterized in acute myeloblastic leukemia (AML) and …

Incidence of 17p deletions and TP53 mutation in myelodysplastic syndrome and acute myeloid leukemia with 5q deletion

A Sebaa, L Ades, F Baran‐Marzack… - Genes …, 2012 - Wiley Online Library
TP53 mutations are frequent in myelodysplastic syndrome (MDS) and acute myeloid
leukemia (AML) with complex karyotype that include del (5q) and are often associated with …

17p− syndrome arising from a novel dicentric translocation in a patient with acute myeloid leukemia

N Watson, L Dunlop, L Robson, P Sharma… - Cancer genetics and …, 2000 - Elsevier
The cytogenetic contribution to the poor prognosis when myelodysplastic syndrome (MDS)
progresses to acute myeloid leukemia (AML) is not well understood. We present a 66-year …