Profiling of aldehyde dehydrogenase isoforms in in vitro formed tumorspheres

I Tsochantaridis, GP Voulgaridou… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Aldehyde dehydrogenases (ALDHs) are considered as markers for normal
and cancer stem cells (CSC) and are involved in cell metabolism, proliferation …

ALDH Activity Assay: A Method for Cancer Stem Cell (CSC) Identification and Isolation

V Del Vecchio, M La Noce, V Tirino - Cancer Stem Cells: Methods and …, 2024 - Springer
Cancer stem cells (CSCs) are a small tumor cell subpopulation, driving cancer initiation,
progression, multidrug resistance, and metastasis. Several methods are used to detect and …

[HTML][HTML] Aldehyde dehydrogenase 1, a potential marker for cancer stem cells in human sarcoma

B Lohberger, B Rinner, N Stuendl, M Absenger… - 2012 - journals.plos.org
Tumors contain a small population of cancer stem cells (CSC) proposed to be responsible
for tumor maintenance and relapse. Aldehyde dehydrogenase 1 (ALDH1) activity has been …

Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer

F Jiang, Q Qiu, A Khanna, NW Todd, J Deepak… - Molecular cancer …, 2009 - AACR
Tumor contains small population of cancer stem cells (CSC) that are responsible for its
maintenance and relapse. Analysis of these CSCs may lead to effective prognostic and …

Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform

P Marcato, CA Dean, CA Giacomantonio, PWK Lee - Cell cycle, 2011 - Taylor & Francis
Recent evidence suggests that enhanced aldehyde dehydrogenase (ALDH) activity is a
hallmark of cancer stem cells (CSC) measurable by the aldefluor assay. ALDH1A1, one of …

[HTML][HTML] Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers

S Deng, X Yang, H Lassus, S Liang, S Kaur, Q Ye, C Li… - PloS one, 2010 - journals.plos.org
Aldehyde dehydrogenase isoform 1 (ALDH1) has been proved useful for the identification of
cancer stem cells. However, our knowledge of the expression and activity of ALDH1 in …

Aldehyde dehydrogenase activity as a functional marker for lung cancer

D Ucar, CR Cogle, JR Zucali, B Ostmark… - Chemico-biological …, 2009 - Elsevier
Aldehyde dehydrogenase (ALDH) activity has been implicated in multiple biological and
biochemical pathways and has been used to identify potential cancer stem cells. Our main …

[HTML][HTML] The ALDH1+ subpopulation of the human NMFH‑1 cell line exhibits cancer stem-like characteristics

D Li, T Zhang, W Gu, P Li, X Cheng… - Oncology …, 2015 - spandidos-publications.com
Cancer stem cells (CSCs) have been reported in many tissues. However, CSCs have yet to
be identified in a human malignant fibrous histiocytoma (MFH) cell line. Elevated aldehyde …

The clinical significance of cancer stem cell markers ALDH1A1 and CD133 in lung adenocarcinoma

T Miyata, T Oyama, T Yoshimatsu, H Higa… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Aldehyde dehydrogenase-1A1 (ALDH1A1) and CD133 have been
identified as markers of cancer stem cells (CSCs). We investigated the expression of these …

[PDF][PDF] ALDH as a stem cell marker in solid tumors

E Toledo-Guzmán Mariel, IH Miguel… - Current stem cell …, 2018 - researchgate.net
Aldehyde dehydrogenase [ALDH] is an enzyme that participates in important cellular
mechanisms as aldehyde detoxification and retinoic acid synthesis; moreover, ALDH activity …