Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure
H Ohno, D Araho, Y Uesawa, H Kagaya… - Anticancer …, 2013 - ar.iiarjournals.org
Background: The mechanism of cytotoxicity induction by flavonoids has been studied by
many investigators, but their tumor specificity is not clear. To address this point, 10 licorice …
many investigators, but their tumor specificity is not clear. To address this point, 10 licorice …
Structure–activity relationships of flavonoid-induced cytotoxicity on human leukemia cells
K Plochmann, G Korte, E Koutsilieri, E Richling… - Archives of biochemistry …, 2007 - Elsevier
The aim of this study was to identify structure elements in flavonoids that are associated with
enhanced cytotoxic activity. We determined the cytotoxicity (EC50) of 23 different flavonoids …
enhanced cytotoxic activity. We determined the cytotoxicity (EC50) of 23 different flavonoids …
Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro
H Chang, M Mi, W Ling, J Zhu, Q Zhang, N Wei… - Archives of pharmacal …, 2008 - Springer
Flavonoids exist extensively in the human diet, and a variety of health effects have been
ascribed to them. The cytotoxic effects of 23 flavonoids on breast cancer cells (MDA-MB-231 …
ascribed to them. The cytotoxic effects of 23 flavonoids on breast cancer cells (MDA-MB-231 …
Quantitative relationships between structure and cytotoxic activity of flavonoid derivatives. An application of Hirshfeld surface derived descriptors
Quantitative relationships between the structure and cytotoxic activity of series flavonoid
derivatives were examined. The first regression-based model, developed for 18 flavanone-2 …
derivatives were examined. The first regression-based model, developed for 18 flavanone-2 …
Molecular mechanisms underlying the anticancer activities of licorice flavonoids
Z Zhang, L Yang, J Hou, S Tian, Y Liu - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Licorice has been commonly used in traditional Chinese
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …
medicine for treatment of gastric, liver, and respiratory disease conditions for more than two …
Flavonoids as anticancer agents: structure-activity relationship study
M Lopez-Lazaro - Current Medicinal Chemistry-Anti-Cancer …, 2002 - ingentaconnect.com
The protection against some forms of cancer provided by many common foods has been
observed in multiple epidemiological studies. Non-nutritive dietary compounds, such as …
observed in multiple epidemiological studies. Non-nutritive dietary compounds, such as …
Discussion on the structural modification and anti-tumor activity of flavonoids
ZG Zhou, DD Li, Y Chen, X Chen… - Current Topics in …, 2022 - ingentaconnect.com
Flavonoids are secondary metabolites of plants. In general# 140; most flavonoids are
combined with glucosides and have extremely complex molecular structures. In nature …
combined with glucosides and have extremely complex molecular structures. In nature …
Antiproliferative activity of flavonoids: influence of the sequential methoxylation state of the flavonoid structure
G Moghaddam, SA Ebrahimi… - Phytotherapy …, 2012 - Wiley Online Library
Dracocephalum kotschyi Boiss. has been used as part of an ethnobotanical remedy against
many forms of human cancer in Iran. It has been demonstrated that a flavonoid named …
many forms of human cancer in Iran. It has been demonstrated that a flavonoid named …
A review on anticancer profile of flavonoids: Sources, chemistry, mechanisms, structure-activity relationship and anticancer activity
Background: Epidemiological studies have suggested that a regular intake of flavonoids is
beneficial for cellular homeostasis and in the prevention of the transformation of normal cells …
beneficial for cellular homeostasis and in the prevention of the transformation of normal cells …
[HTML][HTML] Research Progress on Structural Modification of Effective Antitumor Active Ingredients in Licorice
C Liu, Q Ma, G Gong, F Su - Molecules, 2023 - mdpi.com
Licorice, a widely used traditional Chinese medicine, contains more than 300 flavonoids and
more than 20 triterpenoids, which have potential medicinal value and can prevent the …
more than 20 triterpenoids, which have potential medicinal value and can prevent the …