First-line treatment of advanced biliary ducts carcinoma: a randomized phase II study evaluating 5-FU/LV plus oxaliplatin (Folfox 4) versus 5-FU/LV (de Gramont …

G Schinzari, E Rossi, G Mambella, A Strippoli… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Few clinical trials are available for advanced biliary tract carcinoma (BTC).
We conducted this randomized phase II clinical trial to explore efficacy and safety of 5 …

FOLFOX-4 regimen or single-agent gemcitabine as first-line chemotherapy in advanced biliary tract cancer

AMT Novarino, MA Satolli, I Chiappino… - American journal of …, 2013 - journals.lww.com
Objectives: We conducted a retrospective cohort study to compare 2 different chemotherapy
regimens for advanced biliary tract cancer (BTC). Methods: Records of patients …

[HTML][HTML] Chemotherapy for advanced biliary tract carcinoma: A meta-analysis of randomized controlled trials

L Chen, C Chen, Y Yen, KW Tam - Medicine, 2016 - journals.lww.com
Background: Although gemcitabine and platinum-based agents (GP) are currently regarded
as the standard chemotherapy for advanced biliary tract cancer (BTC), the prognosis …

[HTML][HTML] Advanced biliary tract carcinomas: a retrospective multicenter analysis of first and second-line chemotherapy

F Fiteni, M Jary, F Monnien, T Nguyen, E Beohou… - BMC …, 2014 - Springer
Abstract Background Gemcitabine/Cisplatin (Gem/CDDP) combination has demonstrated a
clear survival advantage over gemcitabine alone and has become a new standard in …

A phase II trial of biweekly oxaliplatin with simplified schedule of 48-h infusion of high-dose 5-fluorouracil and leucorvin for advanced biliary tract carcinoma

JS Chen, Y Chao, TS Yang, WC Chou, LT Chen… - Cancer chemotherapy …, 2009 - Springer
Purpose Advanced biliary tract carcinoma (BTC) is a dismal disease with no standard
chemotherapy. We investigated efficacy and toxicity of biweekly oxaliplatin with 48-h …

Identification of active chemotherapy regimens in advanced biliary tract carcinoma: a review of chemotherapy trials in the past two decades

SV Ulahannan, OE Rahma, AG Duffy… - Hepatic …, 2015 - Future Medicine
Biliary tract carcinoma is a rare malignancy. We performed a comprehensive analysis of
published prospective clinical trials in advanced biliary tract carcinoma in an attempt to …

[HTML][HTML] Feasibility and benefits of second-line chemotherapy in advanced biliary tract cancer: a large retrospective study

T Walter, AM Horgan, M McNamara, L McKeever… - European Journal of …, 2013 - Elsevier
INTRODUCTION: First-line chemotherapy (CT1) is effective in advanced biliary tract cancer
(ABTC). The benefits of second-line chemotherapy (CT2) are unclear. METHODS: We …

[HTML][HTML] Optimization of 5-fluorouracil (5-FU)/cisplatin combination chemotherapy with a new schedule of leucovorin, 5-FU and cisplatin (LV5FU2-P regimen) in …

J Taieb, E Mitry, V Boige, P Artru, J Ezenfis, T Lecomte… - Annals of oncology, 2002 - Elsevier
Background Unresectable biliary tract carcinoma (BTC) is associated with a very poor
prognosis. To improve efficacy and tolerance of the 5-fluorouracil (5-FU)/cisplatin …

A phase II FOLFOX-4 regimen as second-line treatment in advanced biliary tract cancer refractory to gemcitabine/cisplatin

S He, J Shen, X Sun, L Liu, J Dong - Journal of chemotherapy, 2014 - Taylor & Francis
Objective: We aimed to evaluate the efficacy and safety of oxaliplatin, 5-fluorouracil (5-FU),
and leucovorin (LV)(FOLFOX-4) as second-line treatment in patients with advanced biliary …

Biliary tract cancers: systemic therapy for advanced disease

FJ Martinez, RT Shroff - Chinese Clinical Oncology, 2020 - cco.amegroups.org
Biliary tract carcinomas (BTC) present with minimal symptoms and thus they are often
diagnosed in advanced stages that require systemic therapy. Unfortunately, if not resected …