Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance
G Aras, D Kanmaz, NUR ÜRER, S Purisa… - Anticancer …, 2013 - ar.iiarjournals.org
Aim: To detect telomerase reverse transcriptase (TERT) expression in tissue and metastatic
and non-metastatic lymph node samples from patients with non-small cell lung cancer; to …
and non-metastatic lymph node samples from patients with non-small cell lung cancer; to …
Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer
H Hara, K Yamashita, J Shinada, H Yoshimura… - Lung cancer, 2001 - Elsevier
Telomerase has been reported to be a novel diagnostic marker for malignant diseases and
has been recently proven to be composed of three main components, hTR (human …
has been recently proven to be composed of three main components, hTR (human …
hTERT expression is a prognostic factor of survival in patients with stage I non-small cell lung cancer
Activation of telomerase plays a critical role in unlimitedproliferation and immortalization of
cells. The purpose of this study was to evaluate the significance of human telomerase …
cells. The purpose of this study was to evaluate the significance of human telomerase …
The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with nonsmall cell lung carcinoma
Y Fujita, T Fujikane, S Fujiuchi… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND The objectives of this study were to evaluate the diagnostic and prognostic
relevance of human telomerase reverse transcriptase (hTERT) detected in situ in patients …
relevance of human telomerase reverse transcriptase (hTERT) detected in situ in patients …
P2-093: The quantification of the catalytic subunit of telomerase in plasma is a prognostic factor in advanced non-small cell lung cancer (NSCLC) patients
Background: Qualitative and quantitative analysis of circulating DNA in blood is a promising
non-invasive diagnostic and prognostic tool. Our aim was to study the association between …
non-invasive diagnostic and prognostic tool. Our aim was to study the association between …
[PDF][PDF] The expression of telomerase reverse transcriptase protein is an independent prognostic marker in early stage non-small cell lung carcinomas
Background: The catalytic subunit of telomerase, hTERT (telomerase reverse transcriptase),
is one of the most important components of telomerase, and performs a pivotal role in the …
is one of the most important components of telomerase, and performs a pivotal role in the …
[HTML][HTML] Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation
A Marchetti, C Pellegrini, F Buttitta, M Falleni… - Laboratory …, 2002 - Elsevier
Telomerase activity and telomerase reverse transcriptase (hTERT) expression are elevated
in human malignancies. We have investigated telomerase activity measured by the …
in human malignancies. We have investigated telomerase activity measured by the …
[CITATION][C] Clinical and prognostic value of hTERT mRNA expression in patients with non-small-cell lung cancer.
M Zalewska-Ziob, K Dobija-Kubica… - Acta Biochimica …, 2017 - ojs.ptbioch.edu.pl
Telomerase, undetectable in normal somatic cells, plays a critical role in carcinogenesis of
the majority of human tumors including lung carcinoma. The aim of our study was to …
the majority of human tumors including lung carcinoma. The aim of our study was to …
[HTML][HTML] Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
S Lantuejoul, JC Soria, D Moro-Sibilot, L Morat… - British journal of …, 2004 - nature.com
Human telomerase reverse transcriptase is a ribonucleoprotein that synthesises telomeric
sequences, which decrease at each cell division. In cancer cells, its activity is linked to …
sequences, which decrease at each cell division. In cancer cells, its activity is linked to …
Increased human telomerase reverse transcriptase (hTERT) mRNA expression but not telomerase activity is related to survival in curatively resected non-small cell …
R Metzger, D Vallbohmer, C Mueller-Tidow… - Anticancer …, 2009 - ar.iiarjournals.org
Background: The purpose of this study was to evaluate the significance of human
telomerase reverse transcriptase (hTERT) mRNA expression and telomerase activity as …
telomerase reverse transcriptase (hTERT) mRNA expression and telomerase activity as …
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