We sought to determine if complete pathological necrosis (pathCR) predicts favorable
oncological outcome in soft tissue sarcoma (STS) patients receiving pre-operative radiation …

Background Limited data exist regarding the radiographic and histologic response of soft
tissue sarcoma (STS) to neoadjuvant radiotherapy (RT). Methods Between February 2000 …

Purpose Neoadjuvant radiotherapy±chemotherapy and wide local excision is an accepted
management of localized soft tissue sarcomas (STS). Necrosis is prognostic for survival in …

BACKGROUND Histologic response to chemotherapy has been shown to be an
independent prognostic factor in patients with osteosarcoma and Ewing sarcoma. However …

Background Locally advanced soft tissue sarcoma (STS) management may include
neoadjuvant or adjuvant treatment by radiotherapy (RT), chemotherapy (CT) or …

Background and Objectives While treatment‐induced tissue necrosis is a well‐documented
predictor of patient survival in malignant bone tumors, its prognostic value in soft tissue …

Background The prognostic role of tumor necrosis following neoadjuvant therapy is
established in bone sarcomas but remains unclear in soft tissue sarcomas (STS). Methods …

11506 Background: The ISG-STS 1001 was an international, randomized, phase III, clinical
trial for localized, high-risk, soft tissue sarcoma comparing neoadjuvant chemotherapy (ChT) …

11012 Background: We sought to determine the prognostic significance of pathologic
complete response (pCR) in soft tissue sarcoma (STS) in patients (pts) receiving …

Purpose: The treatment of soft tissue sarcomas of the extremity with radiation therapy and
limb sparing surgery results in local control rates of greater than 90%. Because of these …