The Prognostic Role of ACO2 in Renal Cell Carcinoma
D Jaworski, A Kowalewski, J Durślewicz… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Renal cell carcinoma (RCC) continues to pose a challenge due to our
limited understanding of its underlying pathophysiology. Aconitase 2 (ACO2) is a …
limited understanding of its underlying pathophysiology. Aconitase 2 (ACO2) is a …
[HTML][HTML] Pan-Cancer analysis shows that ACO2 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including hepatocellular …
Z Wang, W Zheng, Z Chen, S Wu, H Chang… - Frontiers in …, 2022 - frontiersin.org
Background Recent evidence increasingly suggests key roles for the tricarboxylic acid cycle
and fatty acid metabolism in tumor progression and metastasis. Aconitase 2 (ACO2) is a …
and fatty acid metabolism in tumor progression and metastasis. Aconitase 2 (ACO2) is a …
[HTML][HTML] Expression of AOX1 predicts prognosis of clear cell renal cell carcinoma
L Xiong, Y Feng, W Hu, J Tan, S Li, H Wang - Frontiers in Genetics, 2021 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is the most prevalent kidney cancer worldwide, and
appropriate cancer biomarkers facilitate early diagnosis, treatment, and prognosis prediction …
appropriate cancer biomarkers facilitate early diagnosis, treatment, and prognosis prediction …
[HTML][HTML] Carbonic anhydrase IX is a clinically significant tissue and serum biomarker associated with renal cell carcinoma
M Takacova, M Bartosova, L Skvarkova… - Oncology …, 2013 - spandidos-publications.com
Abstract Carbonic anhydrase IX (CA IX) is regarded as one of the most prominent markers of
tumor hypoxia with potential to serve as a diagnostic biomarker, prognostic indicator as well …
tumor hypoxia with potential to serve as a diagnostic biomarker, prognostic indicator as well …
Decreased expression of the mitochondrial metabolic enzyme aconitase (ACO2) is associated with poor prognosis in gastric cancer
Alterations in energy metabolism play a major role in cancer development. Aconitase
(ACO2) is an essential enzyme located in the mitochondria and catalyzes the …
(ACO2) is an essential enzyme located in the mitochondria and catalyzes the …
[HTML][HTML] Acyl-CoA thioesterase 8 and 11 as novel biomarkers for clear cell renal cell carcinoma
CL Xu, L Chen, D Li, FT Chen, ML Sha, Y Shao - Frontiers in genetics, 2020 - frontiersin.org
Background Clear cell renal cell carcinoma (ccRCC) is essentially a metabolic disorder
characterized by reprogramming of several metabolic pathways. Acyl-coenzyme A …
characterized by reprogramming of several metabolic pathways. Acyl-coenzyme A …
[HTML][HTML] Carbonic Anhydrase IX is not a predictor of outcomes in non-metastatic clear cell renal cell carcinoma-a digital analysis of tissue microarray
M Zerati, KRM Leite, J Pontes-Junior, CC Segre… - International braz j …, 2013 - SciELO Brasil
Introduction The knowledge about the molecular biology of clear cell renal cell carcinoma
(ccRCC) is evolving, and Carbonic Anhydrase type IX (CA-IX) has emerged as a potential …
(ccRCC) is evolving, and Carbonic Anhydrase type IX (CA-IX) has emerged as a potential …
[HTML][HTML] Loss of mitochondrial aconitase promotes colorectal cancer progression via SCD1-mediated lipid remodeling
X You, J Tian, H Zhang, Y Guo, J Yang, C Zhu… - Molecular …, 2021 - Elsevier
Objective Mitochondrial aconitase (ACO2) is an essential enzyme that bridges the TCA cycle
and lipid metabolism. However, its role in cancer development remains to be elucidated …
and lipid metabolism. However, its role in cancer development remains to be elucidated …
Carbonic anhydrase IX (CAIX) expression predicts for renal cell cancer (RCC) patient response and survival to IL-2 therapy
4512 Background: RCC response to IL-2 Rx and patient (pt) survival have been correlated
to histology including the presence of clear cell and alveolar and the absence of papillary …
to histology including the presence of clear cell and alveolar and the absence of papillary …
Acetyl-CoA synthetase 2 enhances tumorigenesis and is indicative of a poor prognosis for patients with renal cell carcinoma
S Zhang, J He, Z Jia, Z Yan, J Yang - Urologic Oncology: Seminars and …, 2018 - Elsevier
Abstract Background Acetyl-CoA synthetase 2 (ACSS2) is highly expressed in various
cancers, whereas ACSS2 expression and function in renal cell carcinoma (RCC) are …
cancers, whereas ACSS2 expression and function in renal cell carcinoma (RCC) are …