A KIT-negative, DOG1-positive epithelioid GIST of the stomach harboring a novel PDGFRA exon 14 single nucleotide deletion
C Rizzardi, S Marzinotto, C Avellini, M Melato… - Anticancer …, 2012 - ar.iiarjournals.org
Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors
of the gastrointestinal tract, and most of them harbor KIT or platelet-derived growth factor …
of the gastrointestinal tract, and most of them harbor KIT or platelet-derived growth factor …
[HTML][HTML] Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases
J Lasota, CL Corless, MC Heinrich, M Debiec-Rychter… - Modern pathology, 2008 - Elsevier
Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms driven by oncogenic,
mutational activation of KIT or platelet-derived growth factor receptor α (PDGFRA). GIST …
mutational activation of KIT or platelet-derived growth factor receptor α (PDGFRA). GIST …
[HTML][HTML] Unexpected reaction of “wild-type” gastrointestinal stromal tumor to imatinib: case report and literature review
Y He, M Da, C Fan, P Tao - Frontiers in Oncology, 2024 - frontiersin.org
Background Most of gastrointestinal stromal tumors (GISTs) are driven by mutations in the
KIT/PDGFRA genes and can benefit from TKIs treatment. However, a small subset of GIST …
KIT/PDGFRA genes and can benefit from TKIs treatment. However, a small subset of GIST …
[HTML][HTML] A Novel Kindred with Familial Gastrointestinal Stromal Tumors Caused by a Rare KIT Germline Mutation (N655K): Clinico-Pathological Presentation and TKI …
M Fornasarig, D Gasparotto, L Foltran… - Journal of Personalized …, 2020 - mdpi.com
Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the
gastrointestinal tract, are characterized by activating mutations in KIT or PDGFRA genes …
gastrointestinal tract, are characterized by activating mutations in KIT or PDGFRA genes …
Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours
J Lasota, M Miettinen - Histopathology, 2008 - Wiley Online Library
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms of
the gastrointestinal tract. Despite clinicopathological differences, GISTs share oncogenic KIT …
the gastrointestinal tract. Despite clinicopathological differences, GISTs share oncogenic KIT …
Gastrointestinal stromal tumors with KIT exon 11 deletions are associated with poor prognosis
J Andersson, P Bümming, JM Meis–Kindblom, H Sihto… - Gastroenterology, 2006 - Elsevier
Background & Aims: Gain-of-function mutations in the KIT receptor tyrosine kinase gene and
rare mutations in the platelet-derived growth factor receptor α (PDGFRA) gene are important …
rare mutations in the platelet-derived growth factor receptor α (PDGFRA) gene are important …
Epithelioid variant of gastrointestinal stromal tumor harboring PDGFRA mutation and MLH1 gene alteration: A case report
Gastrointestinal stromal tumors (GISTs) are the most important and common mesenchymal
tumors of the gastrointestinal tract, especially in the stomach. GISTs are usually driven by …
tumors of the gastrointestinal tract, especially in the stomach. GISTs are usually driven by …
[HTML][HTML] Identification of new tumor-related gene mutations in Chinese gastrointestinal stromal tumors
Y Feng, S Yao, Z Pu, H Cheng, B Fei, J Zou… - Frontiers in Cell and …, 2021 - frontiersin.org
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the
gastrointestinal tract. As the main GIST drivers, gain-of-function mutations in KIT or PDGFRA …
gastrointestinal tract. As the main GIST drivers, gain-of-function mutations in KIT or PDGFRA …
Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing
JF Hechtman, A Zehir, T Mitchell… - Genes …, 2015 - Wiley Online Library
Among gastrointestinal stromal tumors (GISTs) of 10–15% are negative for KIT and
PDGFRA, and most of these cases are SDH deficient. Recent studies have provided data on …
PDGFRA, and most of these cases are SDH deficient. Recent studies have provided data on …
[HTML][HTML] Therapeutic strategies for wild-type gastrointestinal stromal tumor: is it different from KIT or PDGFRA-mutated GISTs?
T Nishida - Translational Gastroenterology and Hepatology, 2017 - ncbi.nlm.nih.gov
Page 2 of 5 Translational Gastroenterology and Hepatology, 2017 be 10/million/year and
GISTs without mutations in KIT and PDGFRA may account for 10–15% of total GISTs …
GISTs without mutations in KIT and PDGFRA may account for 10–15% of total GISTs …