Tumor-associated macrophages facilitate bladder cancer progression by increasing cell growth, migration, invasion and cytokine expression

CP Huang, LX Liu, CR Shyr - Anticancer research, 2020 - ar.iiarjournals.org
Background/Aim: Interactions between stromal and tumor cells in tumor microenvironment
contribute to tumor progression. In bladder cancer (BCa), infiltration of macrophages in …

[HTML][HTML] Tumour-associated macrophages mediate the invasion and metastasis of bladder cancer cells through CXCL8

H Wu, X Zhang, D Han, J Cao, J Tian - PeerJ, 2020 - peerj.com
Tumour-associated macrophages (TAMs) are associated with both the progression and poor
prognosis of a variety of solid tumours. This study aimed to investigate and clarify the tumour …

[HTML][HTML] CXCL1-mediated interaction of cancer cells with tumor-associated macrophages and cancer-associated fibroblasts promotes tumor progression in human …

M Miyake, S Hori, Y Morizawa, Y Tatsumi, Y Nakai… - Neoplasia, 2016 - Elsevier
Tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) are
reported to be associated with poor prognosis, depending on their pro-tumoral roles. Current …

[HTML][HTML] Tumor‑infiltrating M2 macrophages driven by specific genomic alterations are associated with prognosis in bladder cancer

Y Xue, L Tong, F LiuAnwei Liu, A Liu… - Oncology …, 2019 - spandidos-publications.com
The present study aimed to explore the mechanism by which the immune landscape of the
tumor microenvironment influences bladder cancer. CIBERSORT and ssGSEA analyses …

NF-κB inhibitor, BAY11-7082, suppresses M2 tumor-associated macrophage induced EMT potential via miR-30a/NF-κB/Snail signaling in bladder cancer cells

Q Zhang, Z Mao, J Sun - Gene, 2019 - Elsevier
Background Chronic inflammatory microenvironment has been shown to play a key role in
initiating tumorigenesis and facilitating malignant progression. Primary tumors surrounded …

Tumor‐associated macrophages promote bladder tumor growth through PI3K/AKT signal induced by collagen

S Qiu, L Deng, X Liao, L Nie, F Qi, K Jin, X Tu… - Cancer …, 2019 - Wiley Online Library
The tumor microenvironment is associated with various tumor progressions, including
cancer metastasis, immunosuppression, and tumor sustained growth. Tumor‐associated …

[HTML][HTML] Prognostic roles of tumor associated macrophages in bladder cancer: a system review and meta-analysis

SQ Wu, R Xu, XF Li, XK Zhao, BZ Qian - Oncotarget, 2018 - ncbi.nlm.nih.gov
Prognostic roles of tumor associated macrophages in bladder cancer: a system review and
meta-analysis - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

[HTML][HTML] High CD204+ tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder

B Wang, H Liu, X Dong, S Wu, H Zeng, Z Liu, D Wan… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Macrophages (Mφs) are a major cell type that can infiltrate solid tumors and exhibit distinct
phenotypes in different tumor microenvironments. This study attempted to investigate the …

Inflammatory cytokines in bladder cancer

P Shadpour, M Zamani, N Aghaalikhani… - Journal of Cellular …, 2019 - Wiley Online Library
The presence of inflammatory cells and their products in the tumor microenvironment plays a
crucial role in the pathogenesis of a tumor. Releasing the cytokines from a host in response …

A review on the role of M2 macrophages in bladder cancer; pathophysiology and targeting

L Sharifi, MR Nowroozi, E Amini, MK Arami… - International …, 2019 - Elsevier
Tumor-associated macrophages (TAMs) which are often referred to as immunosuppressive
cells (M2 macrophage), constitute a subset of tumor microenvironment cells and affect tumor …