Long-term prognostic impact of chromosome abnormalities in clear cell renal cell carcinoma

C Palumbo, M Furlan, P Balzarini, T Zanotelli… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Clear cell renal cell carcinoma (ccRCC) shows variable chromosomal
abnormalities. The aim of this study was to assess the prognostic role of ccRCC …

Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma

T Klatte, PN Rao, M De Martino… - Journal of clinical …, 2009 - ascopubs.org
Purpose The majority of cytogenetic studies in renal cell carcinoma (RCC) have been
impaired by small sample size, retrospective character, and lack of a survival end point. We …

Histologic prognostic factors associated with chromosomal imbalances in a contemporary series of 89 clear cell renal cell carcinomas

J Dagher, F Dugay, G Verhoest, F Cabillic, S Jaillard… - Human pathology, 2013 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cancer. The aim of
this study was to define specific chromosomal imbalances in ccRCC that could be related to …

Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: Gain of 5q31–qter predicts a distinct clinical phenotype with favorable prognosis

B Gunawan, W Huber, M Holtrup, A von Heydebreck… - Cancer research, 2001 - AACR
To evaluate the prognostic significance of cytogenetic findings in clear cell renal cell
carcinoma (RCC), cytogenetic results of 118 primary RCCs were evaluated in relation to …

Prognostic value of cytogenetic analysis in clear cell renal carcinoma: a study on 131 patients with long-term follow-up

A Antonelli, N Arrighi, R Tardanico… - Anticancer …, 2010 - ar.iiarjournals.org
Background and Aims: Cytogenetic analysis has a role in diagnosis of conventional renal
cell carcinoma, but its role in prognosis is still matter of debate. This study reviews the …

Identification of genomic alterations associated with metastasis and cancer specific survival in clear cell renal cell carcinoma

J Sanjmyatav, K Junker, S Matthes, M Muehr… - The Journal of …, 2011 - Elsevier
PURPOSE: We identified regions of DNA copy number changes that are significantly
associated with metastasis and clinical outcome in patients with clear cell renal cell …

[HTML][HTML] Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers

S Gulati, P Martinez, T Joshi, NJ Birkbak, CR Santos… - European urology, 2014 - Elsevier
Background Candidate biomarkers have been identified for clear cell renal cell carcinoma
(ccRCC) patients, but most have not been validated. Objective To validate published ccRCC …

[HTML][HTML] Pathological and genetic markers improve recurrence prognostication with the University of California Los Angeles Integrated Staging System for patients with …

N Kroeger, C Lebacle, J Hein, PN Rao, R Nejati… - European Journal of …, 2022 - Elsevier
Purpose To elucidate which patients with clear cell renal cell carcinoma have the highest
risk for disease relapse after curative nephrectomy is challenging but is acutely relevant in …

Identification of prognostic genomic markers in patients with localized clear cell renal cell carcinoma (ccRCC).

BI Rini, M Zhou, H Aydin, P Elson, T Maddala… - Journal of Clinical …, 2010 - ascopubs.org
4501 Background: Tumor gene expression may impact prognosis following surgery for early
stage ccRCC. Genomic analysis may also aid in understanding disease biology. Methods …

Copy number alterations with prognostic potential in clear cell renal cell carcinoma

M Maruschke, D Koczan, B Ziems… - Urologia …, 2018 - karger.com
Objectives: To detect chromosomal aberrations in a genome-wide manner with potential
value for prognosis in groups of patients with different histopathological grading in clear cell …