Background: Some ligands of pattern recognition receptors (PRR) are present on tumour
cells. The role of PRR in signalling for cytokine and reactive oxygen intermediates (ROI) …

Objective: This study addressed the role of the pattern recognition receptors (PRR), which
recognize different molecular structures present on microorganisms, apoptotic, senescent …

Although some in vitro studies indicate that macrophages exert cytotoxic responses against
tumour cells by production of reactive oxygen intermediates (ROI), no obvious impairment of …

Antitumor properties and participation in inflammatory events are important characteristics of
activated macrophages. We show here that both antitumor cytostatic function of …

The present study was aimed at characterizing the effects of in vitro exposure to GM‐CSF on
blood monocytes and tumor‐associated macrophages (TAM) in human ovarian cancer …

The innate immune system is an integral component of the inflammatory response to
pathophysiological stimuli. Toll-like receptors (TLRs) and inflammasomes are the major …

Pattern recognition receptors (PRRs) are known for many years for their role in the
recognition of microbial products and the subsequent activation of the immune system. The …

We examined the effect of purified human C-reactive protein (CRP) on induction of human
peripheral blood monocyte (Mo)-mediated cytotoxicity (CTX) and oxidative metabolism …

Antibody-dependent cellular cytotoxicity (ADCC) has been suggested to be an important
defense mechanism against tumors. The effects of recombinant human macrophage colony …

Murine macrophages from different anatomical sites were compared for their ability to
become tumoricidal and to secrete interleukin‐l (IL‐I) and tumor necrosis factor (TNF) …