Cancer-derived exosomes activate immune surveillance and suppress peritoneal metastasis of murine colonic cancer

A Tokuda, T Miyake, D Yasukawa, D Ikuta… - Anticancer …, 2021 - ar.iiarjournals.org
Background: Colonic cancer is associated with a low incidence of peritoneal metastasis
compared with gastric cancer; however, the reason for this remains unclear. In this study, a …

[HTML][HTML] Exosomes derived from colon cancer cells promote tumor progression and affect the tumor microenvironment

M Kim, IT Son, GT Noh, SY Woo, RA Lee… - Journal of Clinical …, 2023 - mdpi.com
Cancer-cell-derived exosomes confer oncogenic properties in their tumor microenvironment
and to other cells; however, the exact mechanism underlying this process is unclear. Here …

Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression

L Wu, X Zhang, B Zhang, H Shi, X Yuan, Y Sun, Z Pan… - Tumor Biology, 2016 - Springer
Exosomes are nano-sized membrane vesicles secreted by both normal and cancer cells.
Emerging evidence indicates that cancer cells derived exosomes contribute to cancer …

[HTML][HTML] Investigation of the roles of exosomes in colorectal cancer liver metastasis

X Wang, X Ding, L Nan, Y Wang… - Oncology …, 2015 - spandidos-publications.com
The leading cause of death among cancer patients is tumor metastasis. Tumor-derived
exosomes are emerging as mediators of metastasis. In the present study, we demonstrated …

[HTML][HTML] 786-0 Renal cancer cell line-derived exosomes promote 786-0 cell migration and invasion in vitro

G Chen, Y Zhang, X Wu - Oncology letters, 2014 - spandidos-publications.com
Emerging evidence indicates that cancer‑derived exosomes contribute to angiogenesis,
tumor immunology and invasion. However, whether cancer cell‑derived exosomes regulate …

[HTML][HTML] Regulation of antitumor immune responses by exosomes derived from tumor and immune cells

A Rincón-Riveros, L Lopez, EV Villegas… - Cancers, 2021 - mdpi.com
Simple Summary A lot of interest has been placed into extracellular vesicles as an
intercellular communication mechanism with potential clinical application. As these vesicles …

[HTML][HTML] Immune suppressed tumor microenvironment by exosomes derived from gastric cancer cells via modulating immune functions

J Liu, S Wu, X Zheng, P Zheng, Y Fu, C Wu, B Lu… - Scientific reports, 2020 - nature.com
Gastric cancer is one of the leading causes of cancer-related death due to late diagnosis
with high metastatic frequency. In this study, the impact of tumor secreted exosomes on …

[HTML][HTML] Tumour-released exosomes and their implications in cancer immunity

M Iero, R Valenti, V Huber, P Filipazzi… - Cell Death & …, 2008 - nature.com
Tumour cells release vesicular structures, defined as microvesicles or exosomes, carrying a
large array of proteins from their originating cell. The expression of antigenic molecules …

[HTML][HTML] Tumor-derived exosomes in colorectal cancer progression and their clinical applications

J Zhou, XL Li, ZR Chen, WJ Chng - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) ranks as the third leading cause of cancer mortality in both of men
and women worldwide due to its metastatic properties and resistance to current treatment …

Crosstalk among colon cancer-derived exosomes, fibroblast-derived exosomes, and macrophage phenotypes in colon cancer metastasis

M Wang, Z Su, PA Barnie - International immunopharmacology, 2020 - Elsevier
Cellular crosstalk is an important mechanism in the pathogenesis of inflammatory disorders
and cancers. One significant means by which cells communicate with each other is through …