Apurinic/Apyrimidinic endonuclease 1 regulates inflammatory response in macrophages

A Jedinak, S Dudhgaonkar, MR Kelley… - Anticancer …, 2011 - ar.iiarjournals.org
The multi-functional apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) DNA repair
and redox signaling protein has been shown to have a role in cancer growth and survival …

Identification of plasma APE1/Ref-1 in lipopolysaccharide-induced endotoxemic rats: implication of serological biomarker for an endotoxemia

MS Park, YR Lee, S Choi, HK Joo, EJ Cho… - Biochemical and …, 2013 - Elsevier
Apurinic/apyrimidinic endonuclease1/Redox factor-1 (APE1/Ref-1) is a multifunctional
protein involved in base excision DNA repair and in transcriptional regulation of gene …

Apurinic/apyrimidinic endonuclease 1 is a key modulator of keratinocyte inflammatory responses

HM Lee, JM Yuk, DM Shin, CS Yang… - The Journal of …, 2009 - journals.aai.org
Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1) functions in both DNA repair
and redox signaling, making it an attractive emerging therapeutic target. However, the role of …

DNA repair and redox activities and inhibitors of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): a comparative analysis and their scope …

G Kaur, RP Cholia, AK Mantha… - Journal of medicinal …, 2014 - ACS Publications
The apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1) is a
multifunctional enzyme involved in DNA repair and activation of transcription factors through …

Apurinic/apyrimidinic endonuclease-1 is associated with angiogenesis and VEGF production via upregulation of COX-2 expression in esophageal cancer tissues

H Nagoya, S Futagami, M Shimpuku… - American Journal …, 2014 - journals.physiology.org
Apurinic/apyrimidinic endonuclease-1 (APE-1) is a key enzyme responsible for DNA base
excision repair and is also a multifunctional protein such as redox effector for several …

Impact of apurinic/apyrimidinic endonuclease 1/redox factor‐1 on treatment response and survival in oral squamous cell carcinoma

KT Hsia, CJ Liu, K Mar, LH Lin, CS Lin… - Head & …, 2016 - Wiley Online Library
Background Apurinic/apyrimidinic endonuclease 1/redox factor‐1 (APE1/Ref‐1) is a
multifunctional protein involved in DNA repair and redox signaling. The purpose of this study …

Cytoplasmic localization and redox cysteine residue of APE1/Ref-1 are associated with its anti-inflammatory activity in cultured endothelial cells

MS Park, CS Kim, HK Joo, YR Lee, G Kang, SJ Kim… - Molecules and …, 2013 - Springer
Apurinic/apyrimidinic endonuclease1/redox factor-1 (APE1/Ref-1) is a multifunctional protein
involved in base excision DNA repair and transcriptional regulation of gene expression …

Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential …

S Yang, K Irani, SE Heffron, F Jurnak… - Molecular cancer …, 2005 - AACR
Abstract Apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) is a
multifunctional protein involved in DNA base excision repair and redox regulation of many …

Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor

C Qian, M Li, J Sui, T Ren, Z Li, L Zhang… - Drug design …, 2014 - Taylor & Francis
The human apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (APE1/Ref-1),
an essential multifunctional protein involved in the repair of oxidative deoxyribonucleic acid …

[HTML][HTML] APE1/Ref-1 role in inflammation and immune response

TT Oliveira, LG Coutinho, LOA de Oliveira… - Frontiers in …, 2022 - frontiersin.org
Apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1) is a
multifunctional enzyme that is essential for maintaining cellular homeostasis. APE1 is the …