CCL2 expression in primary ovarian carcinoma is correlated with chemotherapy response and survival outcomes

AN Fader, N Rasool, SAJ Vaziri, T Kozuki… - Anticancer …, 2010 - ar.iiarjournals.org
CCL2, a chemokine, is expressed in normal human ovarian epithelium but down-regulated
in ovarian adenocarcinomas. The association of CCL2 expression with chemotherapy …

[HTML][HTML] Reduced expression of chemokine (CC motif) ligand-2 (CCL2) in ovarian adenocarcinoma

JM Arnold, PR Huggard, M Cummings… - British journal of …, 2005 - nature.com
Abstract Chemokine (CC motif) ligand-2 (CCL2) is a chemoattractant and activator of
macrophages and is a key determinant of the macrophage infiltrate into tumours. We …

Analysis of CC chemokine and chemokine receptor expression in solid ovarian tumours

C Scotton, D Milliken, J Wilson, S Raju… - British journal of …, 2001 - nature.com
To understand the chemokine network in a tissue, both chemokine and chemokine receptor
expression should be studied. Human epithelial ovarian tumours express a range of …

[HTML][HTML] Overexpressing the CCL2 chemokine in an epithelial ovarian cancer cell line results in latency of in vivo tumourigenicity

P Wojnarowicz, K Gambaro, M De Ladurantaye… - Oncogenesis, 2012 - nature.com
The frequent loss of heterozygosity of chromosome (Chr) 17 in epithelial ovarian cancer
(EOC), particularly high-grade ovarian serous carcinomas (HGOSCs), has been attributed to …

Expression and histopathological correlation of CCR9 and CCL25 in ovarian cancer

R Singh, CR Stockard, WE Grizzle… - International …, 2011 - spandidos-publications.com
Ovarian carcinoma is the most lethal gynecological malignancy among women and its poor
prognosis is mainly due to metastasis. Chemokine receptor CCR9 is primarily expressed by …

[HTML][HTML] Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers

F Moisan, EB Francisco, A Brozovic, GE Duran… - Molecular …, 2014 - Elsevier
Ovarian cancer is associated with a leukocyte infiltrate and high levels of chemokines such
as CCL2. We tested the hypothesis that CCL2 inhibition can enhance chemotherapy with …

Purification of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer

W Liu, L Wang, J Zhang, L Qiao, Y Liu, X Yang… - 3 Biotech, 2021 - Springer
Abstract Chemokine (CC-motif) ligand 2 (CCL2) is an inflammatory cytokine that regulates
the infiltration and migration of monocytes. It is highly expressed by both tumor and stromal …

[HTML][HTML] CCL2 overexpression is associated with paclitaxel resistance in ovarian cancer cells via autocrine signaling and macrophage recruitment

YI Yang, YY Wang, JH Ahn, BH Kim, JH Choi - Biomedicine & …, 2022 - Elsevier
Tumor cells can secret various cytokines and chemokines, which affect the tumor cells
themselves and the neighboring cells. Here, we observed that human ovarian cancer (OC) …

[HTML][HTML] CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion

EL Johnson, R Singh, S Singh… - World journal of surgical …, 2010 - Springer
Abstract Background Ovarian carcinoma (OvCa) is the most lethal gynecological malignancy
among women and its poor prognosis is mainly due to metastasis. Chemokine receptor …

[HTML][HTML] Identification of the Chemokine CX3CL1 as a New Regulator of Malignant Cell Proliferation in Epithelial Ovarian Cancer

F Gaudin, S Nasreddine, AC Donnadieu, D Emilie… - PloS one, 2011 - journals.plos.org
Background Little is known about the molecules that contribute to the growth of epithelial
ovarian carcinomas (EOC), which remain the most lethal gynecological cancer in women …