Differences in urinary renal failure biomarkers in cancer patients initially treated with cisplatin

A Maeda, H Ando, T Ura, K Muro, M Aoki… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: We investigated whether measuring the excretion of each acute kidney
injury (AKI) biomarker after cisplatin (CDDP) administration is useful for predicting AKI and …

Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients

H Shinke, S Masuda, Y Togashi, Y Ikemi… - Cancer chemotherapy …, 2015 - Springer
Purpose Acute kidney injury (AKI) is a common and serious adverse effect of cisplatin-based
chemotherapy. However, traditional markers of kidney function, such as serum creatinine …

Urinary tubular protein-based biomarkers in the rodent model of cisplatin nephrotoxicity: a comparative analysis of serum creatinine, renal histology, and urinary KIM-1 …

V Sinha, LM Vence… - Journal of investigative …, 2013 - journals.sagepub.com
Background Several biomarkers are becoming available for the early detection of acute
kidney injury (AKI), but few have been directly compared. Objective To compare urinary …

Evaluation of urinary neutrophil gelatinase-associated lipocalin and urinary kidney injury molecule-1 as biomarkers of renal function in cancer patients treated with …

E Ghadrdan, S Ebrahimpour… - Journal of Oncology …, 2020 - journals.sagepub.com
Introduction Cisplatin-associated acute kidney injury (AKI) is the major limitation to the use of
cisplatin-based chemotherapy regimens. Serum creatinine as a traditional marker did not …

[HTML][HTML] The Value of Urinary NGAL, KIM-1, and IL-18 Measurements in the Early Detection of Kidney Injury in Oncologic Patients Treated with Cisplatin-Based …

D Szumilas, AJ Owczarek, A Brzozowska… - International Journal of …, 2024 - mdpi.com
Cisplatin is still a widely used anticancer drug characterized by significant nephrotoxicity.
Acute kidney injury (AKI), diagnosed based on the Kidney Disease: Improving Global …

Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy

B George, MS Joy… - Experimental Biology and …, 2018 - journals.sagepub.com
Despite recent progress in the development of novel approaches to treat cancer, traditional
antineoplastic drugs, such as cisplatin, remain a mainstay of regimens targeting solid …

The efficacy of theophylline in preventing cisplatin-related nephrotoxicity in patients with cancer

LD Karademir, F Dogruel, I Kocyigit, C Yazici, A Unal… - Renal failure, 2016 - Taylor & Francis
Objective: Cisplatin is a potent antineoplastic agent used and its major limiting side effect is
nephrotoxicity. The aims of the study are early detection of acute kidney injury (AKI) with …

[HTML][HTML] Urinary neutrophil gelatinase-associated lipocalin levels predict cisplatin-induced acute kidney injury better than albuminuria or urinary cystatin C levels

HYH Lin, SC Lee, SF Lin, HH Hsiao, YC Liu… - The Kaohsiung journal …, 2013 - Elsevier
Cisplatin-induced acute kidney injury (AKI) is a major concern among clinicians in
prescribing cisplatin-based chemotherapy. This study evaluated and compared the ability of …

Profiling of kidney injury biomarkers in patients receiving cisplatin: time‐dependent changes in the absence of clinical nephrotoxicity

B George, X Wen, N Mercke, M Gomez… - Clinical …, 2017 - Wiley Online Library
The success of cisplatin‐containing regimens to treat solid tumors is limited, in part, by
nephrotoxicity. In rodents, several urinary proteins have emerged that are sensitive …

[HTML][HTML] Assessment of renal function in head and neck cancer patients treated with cisplatin: different biomarkers and acute kidney injury classifications

N de Godoy Torso, MB Visacri, JCF Quintanilha… - International journal of …, 2022 - mdpi.com
Cisplatin is associated with dose-limiting nephrotoxicity, and the timely detection of acute
kidney injury (AKI) can affect morbimortality. Therefore, this study aimed to investigate the …