[HTML][HTML] Adenovirus as a vector and oncolytic virus

W Matsunaga, A Gotoh - Current Issues in Molecular Biology, 2023 - mdpi.com
Adenoviral vectors, both oncolytic viruses and gene delivery vectors, are among the earliest
approved and commercialised vectors for gene therapy. Adenoviruses have high cytotoxicity …

Cancer cell-specific gene disruption of VEGF-A using Cas9

W Matsunaga, A Gotoh - Personalized Medicine Universe, 2023 - jstage.jst.go.jp
Purpose: Angiogenesis inhibitor therapy for cancer is an efficient treatment as a" starvation
tactic" against tumor tissues. Angiogenesis inhibitors, such as bevacizumab (avastin), a …

[HTML][HTML] Improving the Transduction Efficiency and Antitumor Effect of Conditionally Replicative Adenovirus by Application of 6-Cyclohexyl Methyl-β-D-maltoside

W Lu, Y Fang, X Meng, X Wang, W Liu, M Liu, P Zhang - Molecules, 2023 - mdpi.com
As a tumor-targeting oncolytic adenovirus (Ad), conditionally replicating adenovirus (CRAd)
can access the cell interior by binding to coxsackievirus-Ad receptors (CARs) and …