[HTML][HTML] Cyclin-dependent kinase inhibitors and their therapeutic potential in colorectal cancer treatment

OM Thoma, MF Neurath, MJ Waldner - Frontiers in Pharmacology, 2021 - frontiersin.org
Cyclin-dependent kinases (CDKs) are key players in cell cycle regulation. So far, more than
ten CDKs have been described. Their direct interaction with cyclins allow progression …

Synergistic and Antagonistic Antiproliferative Effects of Ribociclib (Lee011) and Irinotecan (SN38) on Colorectal Cancer Cells

CI Huang, YK Huang, HM Lee, JH Chen… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Colorectal cancer (CRC) is one of the most common malignancies and
cause of cancer-related deaths worldwide. The combination of chemotherapeutics working …

Cyclin-dependent kinases as potential targets for colorectal cancer: past, present and future

SM Manohar - Future Medicinal Chemistry, 2022 - Future Science
Colorectal cancer (CRC) is a common cancer in the world and its prevalence is increasing in
developing countries. Deregulated cell cycle traverse is a hallmark of malignant …

Anti-Cancer Effects of CDK4/6 Inhibitor LEE011 and Chemotherapy Drugs on Lymphocytic Leukemia L1210 Cells

YC Lin, YH Lin, YU Chang, YC Su, WC Hsieh… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Chronic lymphocytic leukemia is a slowly-progressing disease in which
symptoms often do not manifest until years after disease onset. In advanced stages, infection …

[PDF][PDF] Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment. Front. Pharmacol. 12: 757120. doi: 10.3389/fphar …

OM Thoma, MF Neurath… - Frontiers in Pharmacology …, 2021 - researchgate.net
Cyclin-dependent kinases (CDKs) are key players in cell cycle regulation. So far, more than
ten CDKs have been described. Their direct interaction with cyclins allow progression …

[HTML][HTML] Identifying the Mutational Profile of ABCB5 Upregulation in Colorectal Cancer: A Comprehensive Database Analysis

RE Sexton, K Danasekaran, HY Khan… - Journal of Cancer …, 2021 - fortuneonline.org
Colorectal cancer (CRC) is a leading cause of cancer related deaths worldwide and the third
leading cause of cancer related deaths in the United States with a 5-year survival rate of …