[HTML][HTML] Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents

E Domínguez-Álvarez, B Rácz, MA Marć… - Drug Resistance …, 2022 - Elsevier
Selenium is an essential trace element that is crucial for cellular antioxidant defense against
reactive oxygen species (ROS). Recently, many selenium-containing compounds have …

The innovative potential of selenium-containing agents for fighting cancer and viral infections

W Ali, R Benedetti, J Handzlik, C Zwergel… - Drug Discovery …, 2021 - Elsevier
Selenium-containing compounds have emerged as a potentially promising treatment for
viral infections and tumor development and dissemination. Selenium per se is often …

[HTML][HTML] Therapeutic benefits of selenium in hematological malignancies

MA Ehudin, U Golla, D Trivedi, SD Potlakayala… - International journal of …, 2022 - mdpi.com
Supplementing chemotherapy and radiotherapy with selenium has been shown to have
benefits against various cancers. This approach has also been shown to alleviate the side …

Synthesis of Indolo[2,1‐a]isoquinolin‐6(5H)‐Ones Derivatives via Fe(OTf)3‐Promoted Tandem Selenylation/Cyclization of 2‐Arylindoles

JR Zhang, HY Liu, T Fan, YY Chen… - Advanced Synthesis & …, 2021 - Wiley Online Library
A practical method for the synthesis of selenylsubstituted indolo [2, 1‐a] isoquinolin‐6 (5H)‐
ones through Fe (OTf) 3‐promoted tandem selenylation/cyclization of 2‐arylindoles was …

[HTML][HTML] Cytotoxicity of synthetic derivatives against breast cancer and multi-drug resistant breast cancer cell lines: A literature-based perspective study

S Sharmin, MM Rahaman, M Martorell… - Cancer Cell …, 2021 - Springer
Cancer is the second most killer worldwide causing millions of people to lose their lives
every year. In the case of women, breast cancer takes away the highest proportion of …

[HTML][HTML] Antiviral, antimicrobial and antibiofilm activity of selenoesters and selenoanhydrides

G Spengler, A Kincses, T Mosolygó, MA Marć, M Nové… - Molecules, 2019 - mdpi.com
Selenoesters and the selenium isostere of phthalic anhydride are bioactive selenium
compounds with a reported promising activity in cancer, both due to their cytotoxicity and …

[HTML][HTML] Seleno-analogs of scaffolds resembling natural products a novel warhead toward dual compounds

N Astrain-Redin, I Talavera, E Moreno, MJ Ramírez… - Antioxidants, 2023 - mdpi.com
Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer's
disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated …

[HTML][HTML] Antimicrobial, anticancer and multidrug-resistant reversing activity of novel oxygen-, sulfur-and selenoflavones and bioisosteric analogues

MA Marć, A Kincses, B Rácz, MJ Nasim, M Sarfraz… - Pharmaceuticals, 2020 - mdpi.com
Multidrug resistance of cancer cells to cytotoxic drugs still remains a major obstacle to the
success of chemotherapy in cancer treatment. The development of new drug candidates …

Synthesis strategies for organoselenium compounds and their potential applications in human life

PP Phadnis - Handbook on Synthesis Strategies for Advanced …, 2021 - Springer
This article describes the prime role of selenium (Se) and its compounds in mammalian
biochemical systems, performing diverse functions like maintenance of health through …

[HTML][HTML] Selectfluor-mediated tandem cyclization of enaminones with diselenides toward the synthesis of 3-selenylated chromones

JH Xia, Q Chen, JW Yuan, WS Shi, LR Yang… - RSC advances, 2023 - pubs.rsc.org
A practical and metal-free approach for the regioselective selenation of chromones
employing Selectfluor reagent under mild conditions is described. The developed method is …