[HTML][HTML] The Role of Peroxiredoxins in Cancer Development
Simple Summary Reactive oxygen species (ROS) are unstable derivatives of oxygen that
are generated naturally as products or biproducts of biological reactions. ROS, such as …
are generated naturally as products or biproducts of biological reactions. ROS, such as …
[HTML][HTML] Effects of antioxidant gene overexpression on stress resistance and malignization in vitro and in vivo: a review
Reactive oxygen species (ROS) are normal products of a number of biochemical reactions
and are important signaling molecules. However, at the same time, they are toxic to cells …
and are important signaling molecules. However, at the same time, they are toxic to cells …
[HTML][HTML] A CRISPR screen identifies redox vulnerabilities for KEAP1/NRF2 mutant non-small cell lung cancer
The redox regulator NRF2 is hyperactivated in a large percentage of non-small cell lung
cancer (NSCLC) cases, which is associated with chemotherapy and radiation resistance. To …
cancer (NSCLC) cases, which is associated with chemotherapy and radiation resistance. To …
Shikonin-induced apoptosis of colon cancer cells is reduced by peroxiredoxin V expression
N Chandimali, HN Sun, LZ Kong, X Zhen… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Colon cancer is the second most common deadliest malignancy in the
world and better understanding of its underlying mechanisms is needed to improve clinical …
world and better understanding of its underlying mechanisms is needed to improve clinical …
[HTML][HTML] Knockdown of Peroxiredoxin V increased the cytotoxicity of non-thermal plasma-treated culture medium to A549 cells
HN Sun, XY Guo, DP Xie, XM Wang, CX Ren… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Administration of non-thermal plasma therapy via the use of plasma-activated medium
(PAM) might be a novel strategy for cancer treatment, as it induces apoptosis by increasing …
(PAM) might be a novel strategy for cancer treatment, as it induces apoptosis by increasing …
Anti-tumor properties of Picrasma quassioides extracts in H-RasG12V liver cancer are mediated through ROS-dependent mitochondrial dysfunction
DP Xie, YX Gong, YH Jin, CX Ren, Y Liu… - Anticancer …, 2020 - ar.iiarjournals.org
Background: Picrasma quassioides (PQ) is a traditional Asian herbal medicine with anti-
tumor properties that can inhibit the viability of HepG2 liver cancer cells. H-Ras is often …
tumor properties that can inhibit the viability of HepG2 liver cancer cells. H-Ras is often …
Screening a redox library identifies the anti-tumor drug Hinokitiol for treating intrahepatic cholangiocarcinoma
Aims: Intrahepatic cholangiocarcinoma (ICC) is a highly malignant and heterogeneous
cancer with a poor prognosis. At present, there is no optimal treatment except for surgical …
cancer with a poor prognosis. At present, there is no optimal treatment except for surgical …
Assessment of potential prognostic value of peroxiredoxin 1 in oral squamous cell carcinoma
Y Shen, H Xu, L Li, Y Lu, M Zhang… - Cancer Management …, 2021 - Taylor & Francis
Purpose The role of the peroxiredoxin (PRDX) family in oral squamous cell carcinoma
(OSCC) remains unclear. This study aimed to investigate the expression of PRDXs and their …
(OSCC) remains unclear. This study aimed to investigate the expression of PRDXs and their …
Peroxiredoxin V Silencing Elevates Susceptibility to Doxorubicin-induced Cell Apoptosis via ROS-dependent Mitochondrial Dysfunction in AGS Gastric Cancer Cells
YZ Jin, YX Gong, Y Liu, DP Xie, CX Ren… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Peroxiredoxin V (Prx V) plays crucial roles in cellular apoptosis and
proliferation in various cancer cells by regulating the cellular reactive oxygen species (ROS) …
proliferation in various cancer cells by regulating the cellular reactive oxygen species (ROS) …
[HTML][HTML] Peroxiredoxin 5 protects HepG2 cells from ethyl β-carboline-3-carboxylate-induced cell death via ROS-dependent MAPK signalling pathways
DP Xie, YX Gong, J Lee, EM Jeong, CX Ren… - Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Peroxiredoxin 5 (PRDX5) is the member of Prxs family, widely reported to be
involved in various types of cell death. We previously found that PRDX5 knockdown …
involved in various types of cell death. We previously found that PRDX5 knockdown …