The tumor microenvironment (TME) consists of numerous biologically relevant elements.
One of the most important components of the TME is the extracellular matrix (ECM). The …

Matrix metalloproteinases (MMPs) play a major role in extracellular matrix remodeling and
are involved in tumor cell invasion. Cancers such as childhood leukemia are characterized …

Abstract Background/Aim: Matrix metalloproteinase-2 (MMP2) has been reported to plays a
critical role in the metastatic behaviors of cancer via regulation of the extracellular matrix …

Background/Aim: Mounting evidence has shown that miRNAs play a critical role in the
regulation of hematopoiesis of cell proliferation and apoptosis as well as in tumorigenesis …

The purpose of our study was to investigate whether genetic variations in lncRNA H19 were
associated with susceptibility to childhood leukemia. Two hundred and sixty-six childhood …

Background/Aim: The roles of microRNAs (miRNAs) in tumorigenesis have attracted a lot of
attention. The current study aimed at examining the association of the miR-196a-2 …

Background/Aim: This study investigated whether genetic variations in cyclin D1 (CCND1)
are associated with susceptibility to childhood acute lymphoblastic leukemia (ALL) …

Background/Aim: Matrix metalloproteinases-11 (MMP-11) overexpression has been
reported in various types of cancer including lung cancer. We aimed to examine the …

Background/Aim: Matrix metalloproteinase 2 (MMP2) is up-regulated in many cancers.
However, the association of MMP2 genotype to nasopharyngeal cancer (NPC) susceptibility …

Background/Aim: Cells suffer from oxidative DNA damage which leads to the accumulation
of 8-oxoguanine (8-oxoG) adducts in our genome that can become carcinogenic. The …