Cancer is one of the most important health problems and the second leading cause of death
worldwide. Despite the advances in oncology, cancer heterogeneity remains challenging to …

Solid tumors can be divided into benign solid tumors and malignant solid tumors in the
academic community, among which malignant solid tumors are called cancers. Cancer is …

The Wnt/β-catenin signaling pathway is associated with the regulation of cancer stem cells,
and it can be driven by epigenetic modifications. Here, we aim to identify epigenetic …

The function and structure of the mammalian epithelial cell layer is maintained by distinct
intercellular adhesion complexes including adherens junctions (AJs), tight junctions, and …

Recently, it has been identified that circRNAs can act as miRNA sponge to regulate gene
expression in various types of cancers, associating them with cancer initiation and …

Genome-wide loss-of-function screens are critical tools to identify novel genetic regulators of
intracellular proteins. However, studying the changes in the organelle-specific expression …

Background Recurrence and metastases are still frequent outcomes after initial tumour
control in women diagnosed with breast cancer. Although therapies are selected based on …

Continuous administration of oxaliplatin, the most widely used first-line chemotherapy drug
for colorectal cancer (CRC), eventually leads to drug resistance. Increasing the sensitivity of …

Background Even though the relevance of microRNA (miR)-302c has been studied, little is
known about its involvement in colon cancer (CC). Aims Our aim here was to investigate the …

Despite intensive efforts, no inhibitors of the Wnt/β-catenin signaling pathway have been
approved so far for the clinical treatment of cancer. We synthesized novel N …