[HTML][HTML] Mechanisms behind context-dependent role of glucocorticoids in breast cancer progression

H Butz, A Patócs - Cancer and Metastasis Reviews, 2022 - Springer
Abstract Glucocorticoids (GCs), mostly dexamethasone (dex), are routinely administered as
adjuvant therapy to manage side effects in breast cancer. However, recently, it has been …

[HTML][HTML] Genome-wide crosstalk between steroid receptors in breast and prostate cancers

V Paakinaho, JJ Palvimo - Endocrine-Related Cancer, 2021 - erc.bioscientifica.com
Steroid receptors (SRs) constitute an important class of signal-dependent transcription
factors (TFs). They regulate a variety of key biological processes and are crucial drug targets …

[HTML][HTML] Steroid receptors in breast cancer: understanding of molecular function as a basis for effective therapy development

W Kowalczyk, G Waliszczak, R Jach… - Cancers, 2021 - mdpi.com
Simple Summary The knowledge we currently possess on the molecular function of steroid
receptors in breast cancer is incredibly vast. New research in the field is constantly …

Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment

CP Kerkvliet, TH Truong, JH Ostrander… - Essays in …, 2021 - portlandpress.com
The classification and treatment of breast cancer is largely defined by the expression of
steroid hormone receptors (HRs), namely estrogen receptor (ER) and progesterone receptor …

[HTML][HTML] Novel Insights into the Role of the Mineralocorticoid Receptor in Human Glioblastoma

P Aldaz, A Fernández-Celis, N López-Andrés… - International Journal of …, 2021 - mdpi.com
The majority of glioblastoma (GBM) patients require the administration of dexamethasone
(DEXA) to reduce brain inflammation. DEXA activates the glucocorticoid receptor (GR) …

The role of mineralocorticoids and glucocorticoids under the impact of 11β-hydroxysteroid dehydrogenase in human breast lesions

M Cai, K McNamara, Y Yamazaki, N Harada… - Medical Molecular …, 2022 - Springer
We attempted to explore the possible involvement of the in situ availability of
mineralocorticoids and mineralocorticoid receptor (MR) in the pathogenesis of mammary …

Mineralocorticoid receptor signaling in Triple-negative Breast Cancer

SH Posani - 2023 - search.proquest.com
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks
expression of hormone receptors and HER2 (Human epidermal growth factor 2) receptor …

Development of a Specialized Zebrafish Xenotransplantation Database and Establishment of Alu-Based Tumor DNA Quantification Method in Zebrafish: Focus On …

S Targen - 2020 - search.proquest.com
Successful xenotransplantation of human cancer cells into zebrafish host marked a new era
in cancer research enabling high throughput in vivo screens. Zebrafish xenotransplantation …

Mineralocorticoid and Glucocorticoid Receptors as Novel Targets in Breast and Liver Cancer Therapies

D Güneş - 2020 - search.proquest.com
Cell signaling is a complex phenomenon and is maintained through intertwined signal
transmissions within and in-between the cells. Anti-cancer therapies are often challenged by …