Chemoradiation-induced mucositis is a debilitating condition of the gastrointestinal tract
eventuating from antineoplastic treatment. It is believed to occur primarily due to oxidative …

Mucositis is a common and most debilitating complication associated with the cytotoxicity of
chemotherapy. The condition affects the entire alimentary canal from the mouth to the anus …

Gamma-glutamyl transpeptidase (GGT) is an enzyme located on the outer membrane of the
cells where it regulates the metabolism of glutathione (GSH), the most abundant intracellular …

γ-Glutamyl transpeptidase (GGT) is an enzyme located on the surface of cellular membranes
and involved in GSH metabolism and maintenance of redox homeostasis. High GGT …

Abstract Gamma-glutamyltransferase 5 (GGT5) is a member of the gamma-glutamyl
transpeptidase gene family with the capacity of cleaving the gamma-glutamyl moiety of …

Animal models are a critical aspect of mucositis research, providing unprecedent insight into
the pathobiology of mucositis. Introduction of tumour-bearing models, cyclic dosing …

Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells that
accumulate in tumor-bearing hosts. Since MDSCs suppress anti-tumor immunity and …

Introduction Despite recent advances, there are limited treatments available for acute
asthma exacerbations. Here, we investigated the therapeutic potential of GGsTop, a γ …

Background and Purpose Hepatic steatosis may be associated with an increased γ‐
glutamyltransferase (γ‐GT) levels. Ischaemia‐reoxygenation (IR) injury causes several …

Background/Aim: Oral mucositis, which occurs frequently in the treatment of cancer, is a
major problem. In this study, we aimed to develop a rat model of oral mucositis induced by …