[HTML][HTML] Interactions of analgesics with cisplatin: Modulation of anticancer efficacy and potential organ toxicity
A El-Sheikh, Z Khired - Medicina, 2021 - mdpi.com
Cisplatin (CDDP), one of the most eminent cancer chemotherapeutic agents, has been
successfully used to treat more than half of all known cancers worldwide. Despite its …
successfully used to treat more than half of all known cancers worldwide. Despite its …
The role of opioids and their receptors in urological malignancy: a review
Purpose: We reviewed the literature surrounding the role of opioids and their receptors in
urological malignancy. Recent studies have suggested clinically significant effects of …
urological malignancy. Recent studies have suggested clinically significant effects of …
d,l-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro
H Oppermann, M Matusova, A Glasow… - Cancer Chemotherapy …, 2019 - Springer
Purpose Glioblastoma (GBM) is the most common malignant tumor of the central nervous
system. Median survival of glioblastoma patients under standard therapy including …
system. Median survival of glioblastoma patients under standard therapy including …
[HTML][HTML] Methadone Requires the Co-Activation of μ-Opioid and Toll-Like-4 Receptors to Produce Extracellular DNA Traps in Bone-Marrow-Derived Mast Cells
FL Martínez-Cuevas, SL Cruz… - International Journal of …, 2024 - mdpi.com
Methadone is an effective and long-lasting analgesic drug that is also used in medication-
assisted treatment for people with opioid use disorders. Although there is evidence that …
assisted treatment for people with opioid use disorders. Although there is evidence that …
[HTML][HTML] Discussion on the benefits of different treatment strategies in elderly and non-elderly patients with appendix MiNEN: a retrospective study based on SEER …
X Xing, Y Zhang, L Wang, Y Wang, Z Zhang… - International Journal of …, 2023 - Springer
Purpose To investigate the benefits of surgery alone and postoperative chemotherapy in
elderly and non-elderly patients with appendiceal mixed neuroendocrine non …
elderly and non-elderly patients with appendiceal mixed neuroendocrine non …
The role of opioids in cancer progression
MF Ramirez, A Gorur, JP Cata - International anesthesiology …, 2020 - journals.lww.com
Cancer is the second most common cause of death in the United States. The vast majority of
cancer-related deaths occur due to metastatic disease, which may be the result of direct …
cancer-related deaths occur due to metastatic disease, which may be the result of direct …
[HTML][HTML] Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent
B Haas, J Ciftcioglu, S Jermar, S Weickhardt… - Journal of Cancer …, 2021 - Springer
Purpose d, l-methadone (MET), an analgesic drug used for pain treatment and opiate
addiction, has achieved attention from oncologists and social media as possible …
addiction, has achieved attention from oncologists and social media as possible …
Methadone enhances the effectiveness of 5‐aminolevulinic acid‐based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro
Although having shown promising clinical outcomes, the effectiveness of 5‐aminolevulinic
acid‐based photodynamic therapy (ALA‐PDT) for squamous cell carcinoma (SCC) and …
acid‐based photodynamic therapy (ALA‐PDT) for squamous cell carcinoma (SCC) and …
[HTML][HTML] Against repurposing methadone for glioblastoma therapy
T Vatter, L Klumpp, K Ganser, N Stransky, D Zips… - Biomolecules, 2020 - mdpi.com
Methadone, which is used as maintenance medication for outpatient treatment of opioid
dependence or as an analgesic drug, has been suggested by preclinical in vitro and mouse …
dependence or as an analgesic drug, has been suggested by preclinical in vitro and mouse …
DL-methadone as an enhancer of chemotherapeutic drugs in head and neck cancer cell lines
V Landgraf, M Griessmann, J Roller… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: The aim of this study was to analyze the effect of DL-methadone on
enhancing the action of the chemotherapeutic drugs cisplatin, doxorubicin, 5-fluoruracil (5 …
enhancing the action of the chemotherapeutic drugs cisplatin, doxorubicin, 5-fluoruracil (5 …